CROCC report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0010669Biological processepithelial structure maintenance
GO_0045494Biological processphotoreceptor cell maintenance
GO_0010457Biological processcentriole-centriole cohesion
GO_0033365Biological processprotein localization to organelle
GO_0032053Biological processciliary basal body organization
GO_0051649Biological processestablishment of localization in cell
GO_0019725Biological processcellular homeostasis
GO_0007098Biological processcentrosome cycle
GO_0045724Biological processpositive regulation of cilium assembly
GO_0051656Biological processestablishment of organelle localization
GO_0008104Biological processprotein localization
GO_1903566Biological processpositive regulation of protein localization to cilium
GO_0097729Cellular component9+2 motile cilium
GO_0005886Cellular componentplasma membrane
GO_0005813Cellular componentcentrosome
GO_0070062Cellular componentextracellular exosome
GO_0001917Cellular componentphotoreceptor inner segment
GO_0035253Cellular componentciliary rootlet
GO_0005814Cellular componentcentriole
GO_0015629Cellular componentactin cytoskeleton
GO_0005829Cellular componentcytosol
GO_0120219Cellular componentsubapical part of cell
GO_0005200Molecular functionstructural constituent of cytoskeleton
GO_0005198Molecular functionstructural molecule activity
GO_0005515Molecular functionprotein binding
GO_0003779Molecular functionactin binding
GO_0019894Molecular functionkinesin binding

IV. Literature review

[source]
Gene nameCROCC
Protein nameCROCC protein
Rootletin (Ciliary rootlet coiled-coil protein)
Ciliary rootlet coiled-coil, rootletin
SynonymsKIAA0445
DescriptionFUNCTION: Major structural component of the ciliary rootlet, a cytoskeletal-like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends proximally toward the cell nucleus (By similarity). Furthermore, is required for the correct positioning of the cilium basal body relative to the cell nucleus, to allow for ciliogenesis . Contributes to centrosome cohesion before mitosis . .

AccessionsENST00000445545.6
A0A087WU09
A0A087WW81
Q5TZA2
A1L0S9
A1L0S8
ENST00000375541.10 [Q5TZA2-1]
B1AKD8
ENST00000467715.2
ENST00000467938.5