CRMP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006139Biological processnucleobase-containing compound metabolic process
GO_0010977Biological processnegative regulation of neuron projection development
GO_0007399Biological processnervous system development
GO_0006208Biological processpyrimidine nucleobase catabolic process
GO_0043204Cellular componentperikaryon
GO_0005813Cellular componentcentrosome
GO_0030496Cellular componentmidbody
GO_0005829Cellular componentcytosol
GO_0005819Cellular componentspindle
GO_0030426Cellular componentgrowth cone
GO_0004157Molecular functiondihydropyrimidinase activity
GO_0031005Molecular functionfilamin binding
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0016812Molecular functionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides

IV. Literature review

[source]
Gene nameCRMP1
Protein nameCRMP1 protein
Collapsin response mediator protein 1, isoform CRA_d (cDNA FLJ37406 fis, clone BRAMY2028282, highly similar to Dihydropyrimidinase-related protein 1)
Collapsin response mediator protein 1 isoform A
Dihydropyrimidinase-related protein 1 (DRP-1) (Collapsin response mediator protein 1) (CRMP-1) (Inactive dihydropyrimidinase) (Unc-33-like phosphoprotein 3) (ULIP-3)
Collapsin response mediator protein 1
Collapsin response mediator protein 1 isoform B
SynonymsDPYSL1
ULIP3
hCG_39896
DescriptionFUNCTION: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton . Plays a role in axon guidance . During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone . Involved in invasive growth and cell migration . May participate in cytokinesis . .

AccessionsB3KT07
Q14194
Q96I11
E9PD68
ENST00000512574.1
ENST00000324989.12 [Q14194-2]
X5DQV1
X5DNI1
ENST00000397890.7 [Q14194-1]