CRLS1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0032049Biological processcardiolipin biosynthetic process
GO_0036148Biological processphosphatidylglycerol acyl-chain remodeling
GO_0097068Biological processresponse to thyroxine
GO_1905711Biological processresponse to phosphatidylethanolamine
GO_0005743Cellular componentmitochondrial inner membrane
GO_0005739Cellular componentmitochondrion
GO_0047144Molecular function2-acylglycerol-3-phosphate O-acyltransferase activity
GO_0003841Molecular function1-acylglycerol-3-phosphate O-acyltransferase activity
GO_0043337Molecular functioncardiolipin synthase (CMP-forming)

IV. Literature review

[source]
Gene nameCRLS1
Protein nameCardiolipin synthase (CMP-forming) (CLS) (EC 2.7.8.41) (Protein GCD10 homolog)
cardiolipin synthase (CMP-forming) (EC 2.7.8.41)
SynonymsCLS1
hCG_39526
C20orf155
DescriptionFUNCTION: Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. .

FUNCTION: Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. .

AccessionsQ9UJA2
ENST00000378868.4 [Q9UJA2-2]
Q6NTG3
ENST00000378863.9 [Q9UJA2-1]
ENST00000452938.5