Name | Number of supported studies | Average coverage | |
---|---|---|---|
adipocyte | 9 studies | 45% ± 11% | |
endothelial cell | 8 studies | 21% ± 5% | |
type I pneumocyte | 7 studies | 25% ± 7% | |
epithelial cell | 5 studies | 40% ± 16% | |
cardiac muscle cell | 5 studies | 23% ± 3% | |
mesothelial cell | 5 studies | 33% ± 10% | |
ciliated cell | 5 studies | 26% ± 7% | |
hepatocyte | 5 studies | 48% ± 19% | |
type II pneumocyte | 5 studies | 26% ± 9% | |
astrocyte | 4 studies | 27% ± 7% | |
glutamatergic neuron | 4 studies | 39% ± 17% | |
oligodendrocyte | 4 studies | 18% ± 2% | |
classical monocyte | 3 studies | 21% ± 5% | |
fibroblast | 3 studies | 21% ± 6% | |
GABAergic neuron | 3 studies | 34% ± 5% | |
oligodendrocyte precursor cell | 3 studies | 25% ± 6% | |
dendritic cell | 3 studies | 19% ± 3% | |
abnormal cell | 3 studies | 33% ± 15% | |
goblet cell | 3 studies | 22% ± 6% | |
intestinal crypt stem cell | 3 studies | 28% ± 4% | |
basal cell | 3 studies | 23% ± 8% | |
neuron | 3 studies | 38% ± 19% | |
microglial cell | 3 studies | 19% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1783.21 | 1445 / 1445 | 100% | 4.10 | 183 / 183 |
ovary | 100% | 2138.48 | 180 / 180 | 99% | 4.55 | 426 / 430 |
stomach | 100% | 3041.55 | 359 / 359 | 89% | 4.65 | 254 / 286 |
intestine | 100% | 2234.55 | 966 / 966 | 71% | 3.88 | 375 / 527 |
lung | 100% | 3897.89 | 578 / 578 | 53% | 1.61 | 611 / 1155 |
prostate | 100% | 3013.34 | 245 / 245 | 47% | 0.82 | 235 / 502 |
liver | 100% | 4922.50 | 226 / 226 | 46% | 0.85 | 188 / 406 |
brain | 100% | 1600.68 | 2630 / 2642 | 44% | 0.74 | 312 / 705 |
kidney | 100% | 3148.34 | 89 / 89 | 43% | 1.32 | 391 / 901 |
bladder | 100% | 2103.95 | 21 / 21 | 39% | 1.73 | 197 / 504 |
pancreas | 100% | 1916.76 | 328 / 328 | 30% | 0.48 | 53 / 178 |
uterus | 100% | 1909.89 | 170 / 170 | 18% | 0.28 | 82 / 459 |
skin | 100% | 1692.04 | 1807 / 1809 | 16% | 0.22 | 75 / 472 |
breast | 100% | 3047.52 | 459 / 459 | 14% | 0.26 | 157 / 1118 |
thymus | 100% | 2336.49 | 653 / 653 | 12% | 0.20 | 75 / 605 |
adrenal gland | 100% | 4676.03 | 258 / 258 | 8% | 0.13 | 19 / 230 |
adipose | 100% | 4151.47 | 1204 / 1204 | 0% | 0 | 0 / 0 |
muscle | 100% | 3485.85 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1650.59 | 241 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1872.70 | 1331 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 3284.02 | 851 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 62% | 896.17 | 576 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 17% | 0.20 | 5 / 29 |
eye | 0% | 0 | 0 / 0 | 13% | 0.18 | 10 / 80 |
tonsil | 0% | 0 | 0 / 0 | 4% | 0.05 | 2 / 45 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0032049 | Biological process | cardiolipin biosynthetic process |
GO_0036148 | Biological process | phosphatidylglycerol acyl-chain remodeling |
GO_0097068 | Biological process | response to thyroxine |
GO_1905711 | Biological process | response to phosphatidylethanolamine |
GO_0005743 | Cellular component | mitochondrial inner membrane |
GO_0005739 | Cellular component | mitochondrion |
GO_0047144 | Molecular function | 2-acylglycerol-3-phosphate O-acyltransferase activity |
GO_0003841 | Molecular function | 1-acylglycerol-3-phosphate O-acyltransferase activity |
GO_0043337 | Molecular function | cardiolipin synthase (CMP-forming) |
Gene name | CRLS1 |
Protein name | Cardiolipin synthase (CMP-forming) (CLS) (EC 2.7.8.41) (Protein GCD10 homolog) cardiolipin synthase (CMP-forming) (EC 2.7.8.41) |
Synonyms | CLS1 hCG_39526 C20orf155 |
Description | FUNCTION: Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. . FUNCTION: Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. . |
Accessions | Q9UJA2 ENST00000378868.4 [Q9UJA2-2] Q6NTG3 ENST00000378863.9 [Q9UJA2-1] ENST00000452938.5 |