CORO7 | OmnibusX

Name	Number of supported studies	Average coverage
CD4-positive, alpha-beta T cell	5 studies	27% ± 6%	Explore
CD8-positive, alpha-beta T cell	5 studies	27% ± 6%	Explore
non-classical monocyte	5 studies	30% ± 14%	Explore
plasmacytoid dendritic cell	5 studies	34% ± 13%	Explore
B cell	4 studies	18% ± 4%	Explore
CD16-positive, CD56-dim natural killer cell, human	4 studies	23% ± 3%	Explore
natural killer cell	4 studies	24% ± 6%	Explore
myeloid cell	4 studies	21% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	28% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	35% ± 10%	Explore
mucosal invariant T cell	3 studies	29% ± 9%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	22% ± 3%	Explore
dendritic cell	3 studies	32% ± 19%	Explore
macrophage	3 studies	22% ± 7%	Explore
oligodendrocyte	3 studies	22% ± 5%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	4 studies	24% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	2673.60	258 / 258	100%	5.39	229 / 230
intestine	100%	3294.14	966 / 966	99%	5.04	524 / 527
kidney	100%	2389.06	89 / 89	99%	4.45	893 / 901
brain	99%	2453.27	2616 / 2642	100%	8.29	705 / 705
uterus	100%	1958.11	170 / 170	99%	4.14	453 / 459
bladder	100%	2079.00	21 / 21	99%	4.65	497 / 504
thymus	100%	2567.49	652 / 653	99%	3.80	597 / 605
stomach	100%	1912.98	359 / 359	98%	4.20	281 / 286
prostate	100%	2590.50	244 / 245	99%	2.44	495 / 502
lung	100%	4785.80	577 / 578	98%	3.48	1135 / 1155
breast	100%	2309.67	459 / 459	98%	3.65	1096 / 1118
esophagus	100%	1881.15	1440 / 1445	97%	2.67	177 / 183
skin	95%	1551.56	1719 / 1809	99%	5.79	469 / 472
pancreas	90%	1049.60	295 / 328	99%	5.13	177 / 178
ovary	94%	1142.44	169 / 180	88%	1.80	377 / 430
liver	71%	705.45	160 / 226	86%	2.39	350 / 406
adipose	100%	2511.32	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	14.94	29 / 29
peripheral blood	100%	9392.26	929 / 929	0%	0	0 / 0
spleen	100%	10132.63	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	4.12	1 / 1
blood vessel	99%	2079.33	1327 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	3.73	44 / 45
eye	0%	0	0 / 0	98%	4.60	78 / 80
heart	94%	1119.16	809 / 861	0%	0	0 / 0
muscle	58%	479.71	465 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0030010	Biological process	establishment of cell polarity
GO_0035332	Biological process	positive regulation of hippo signaling
GO_0015031	Biological process	protein transport
GO_0030041	Biological process	actin filament polymerization
GO_0007030	Biological process	Golgi organization
GO_0016477	Biological process	cell migration
GO_0006895	Biological process	Golgi to endosome transport
GO_0005802	Cellular component	trans-Golgi network
GO_0000139	Cellular component	Golgi membrane
GO_0005829	Cellular component	cytosol
GO_0005794	Cellular component	Golgi apparatus
GO_0031410	Cellular component	cytoplasmic vesicle
GO_0016020	Cellular component	membrane
GO_0005515	Molecular function	protein binding
GO_0003779	Molecular function	actin binding

IV. Literature review

[source]

Gene name	CORO7
Protein name	Coronin-7 (Crn7) (70 kDa WD repeat tumor rejection antigen homolog) Coronin-7 Coronin
Synonyms
Description	FUNCTION: F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking. May play a role in the maintenance of the Golgi apparatus morphology. . FUNCTION: F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking. May play a role in the maintenance of the Golgi apparatus morphology. . FUNCTION: F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking. May play a role in the maintenance of the Golgi apparatus morphology. . FUNCTION: F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking. May play a role in the maintenance of the Golgi apparatus morphology. . FUNCTION: F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking. May play a role in the maintenance of the Golgi apparatus morphology. . FUNCTION: F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking. May play a role in the maintenance of the Golgi apparatus morphology. .
Accessions	ENST00000572153.5 P57737 ENST00000575850.5 ENST00000572898.1 ENST00000631578.1 ENST00000633889.1 ENST00000614702.4 [P57737-1] I3L0X8 I3L1T5 I3L212 ENST00000631678.1 ENST00000632603.1 ENST00000631757.1 I3L359 ENST00000570645.5 ENST00000573165.1 ENST00000632167.1 ENST00000632164.1 ENST00000631809.1 ENST00000574025.5 [P57737-2] I3L1G9 ENST00000576637.1 ENST00000572044.1 I3L1M1 ENST00000617235.2 [P57737-4] ENST00000631534.1 [P57737-2] ENST00000632177.1 ENST00000251166.9 [P57737-1] ENST00000576051.5 I3L482 ENST00000574311.5 I3L351 ENST00000634048.1 E7EP81 I3L2Y6 ENST00000633467.1 I3L0Z7 ENST00000571756.5 ENST00000570779.1 I3L258 ENST00000576437.5 I3L442 ENST00000571052.5 I3L426 I3NI06 ENST00000572549.5 ENST00000571227.5 ENST00000633681.1 I3L2S7 ENST00000632515.1 ENST00000570928.5 ENST00000537233.6 [P57737-4] ENST00000633070.1 I3L1Z1 ENST00000632270.1 ENST00000575038.5 ENST00000631960.1 ENST00000571059.5 ENST00000632158.1 I3L423 ENST00000633804.1

CORO7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review