Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 16 studies | 46% ± 19% | |
fibroblast | 11 studies | 24% ± 9% | |
endothelial cell | 7 studies | 25% ± 5% | |
smooth muscle cell | 7 studies | 22% ± 4% | |
glutamatergic neuron | 4 studies | 33% ± 13% | |
retinal ganglion cell | 4 studies | 53% ± 26% | |
epithelial cell | 4 studies | 41% ± 16% | |
pericyte | 4 studies | 22% ± 3% | |
endothelial cell of vascular tree | 4 studies | 19% ± 2% | |
deuterosomal cell | 3 studies | 36% ± 0% | |
pancreatic A cell | 3 studies | 32% ± 7% | |
pancreatic D cell | 3 studies | 39% ± 16% | |
type B pancreatic cell | 3 studies | 42% ± 20% | |
neuron | 3 studies | 28% ± 12% | |
retinal cone cell | 3 studies | 33% ± 9% | |
GABAergic neuron | 3 studies | 26% ± 5% | |
basal cell | 3 studies | 25% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 1403.58 | 226 / 226 | 100% | 92.45 | 406 / 406 |
ovary | 100% | 1932.23 | 180 / 180 | 100% | 63.64 | 430 / 430 |
kidney | 100% | 1938.89 | 89 / 89 | 100% | 78.93 | 900 / 901 |
brain | 100% | 3408.09 | 2639 / 2642 | 100% | 132.40 | 705 / 705 |
thymus | 100% | 2710.47 | 653 / 653 | 100% | 122.22 | 604 / 605 |
uterus | 100% | 1789.79 | 170 / 170 | 100% | 98.63 | 458 / 459 |
skin | 100% | 1400.69 | 1802 / 1809 | 100% | 109.14 | 472 / 472 |
prostate | 100% | 2495.91 | 244 / 245 | 100% | 141.09 | 502 / 502 |
stomach | 100% | 1685.28 | 358 / 359 | 100% | 66.44 | 285 / 286 |
breast | 100% | 2017.26 | 459 / 459 | 99% | 97.17 | 1109 / 1118 |
adrenal gland | 100% | 1747.29 | 258 / 258 | 99% | 87.14 | 228 / 230 |
lung | 99% | 1396.04 | 574 / 578 | 100% | 70.68 | 1152 / 1155 |
bladder | 100% | 2269.90 | 21 / 21 | 99% | 87.25 | 497 / 504 |
esophagus | 99% | 2081.38 | 1432 / 1445 | 99% | 52.64 | 182 / 183 |
intestine | 99% | 2530.57 | 956 / 966 | 99% | 70.42 | 523 / 527 |
pancreas | 96% | 896.90 | 316 / 328 | 100% | 72.98 | 178 / 178 |
adipose | 100% | 1969.31 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 100.12 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 93.83 | 29 / 29 |
tonsil | 0% | 0 | 0 / 0 | 100% | 69.43 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 57.48 | 1 / 1 |
blood vessel | 100% | 3028.33 | 1333 / 1335 | 0% | 0 | 0 / 0 |
spleen | 99% | 984.64 | 239 / 241 | 0% | 0 | 0 / 0 |
muscle | 98% | 1205.80 | 789 / 803 | 0% | 0 | 0 / 0 |
heart | 97% | 1534.99 | 834 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 20% | 188.87 | 183 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006338 | Biological process | chromatin remodeling |
GO_0007517 | Biological process | muscle organ development |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005886 | Cellular component | plasma membrane |
GO_0005634 | Cellular component | nucleus |
GO_0005515 | Molecular function | protein binding |
GO_0042393 | Molecular function | histone binding |
Gene name | COPRS |
Protein name | Coordinator of PRMT5 and differentiation stimulator (Cooperator of PRMT5) (Protein TTP1) Coordinator of PRMT5 and differentiation stimulator |
Synonyms | COPR5 C17orf79 |
Description | FUNCTION: Histone-binding protein required for histone H4 methyltransferase activity of PRMT5. Specifically required for histone H4 'Arg-3' methylation mediated by PRMT5, but not histone H3 'Arg-8' methylation, suggesting that it modulates the substrate specificity of PRMT5. Specifically interacts with the N-terminus of histone H4 but not with histone H3, suggesting that it acts by promoting the association between histone H4 and PRMT5. Involved in CCNE1 promoter repression. Plays a role in muscle cell differentiation by modulating the recruitment of PRMT5 to the promoter of genes involved in the coordination between cell cycle exit and muscle differentiation (By similarity). . |
Accessions | J3QRX9 J3QRX6 ENST00000496655.1 ENST00000579741.1 ENST00000302362.11 H9KV77 ENST00000378634.6 Q9NQ92 ENST00000579984.1 J3QRX4 |