Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte precursor cell | 16 studies | 75% ± 16% | |
astrocyte | 15 studies | 63% ± 22% | |
glutamatergic neuron | 13 studies | 79% ± 20% | |
GABAergic neuron | 11 studies | 68% ± 23% | |
oligodendrocyte | 8 studies | 32% ± 19% | |
neuron | 7 studies | 44% ± 19% | |
retinal ganglion cell | 7 studies | 64% ± 24% | |
endothelial cell | 6 studies | 51% ± 17% | |
interneuron | 6 studies | 69% ± 26% | |
microglial cell | 5 studies | 38% ± 18% | |
amacrine cell | 5 studies | 41% ± 10% | |
retinal cone cell | 5 studies | 60% ± 27% | |
fibroblast | 5 studies | 27% ± 10% | |
granule cell | 4 studies | 88% ± 4% | |
retinal pigment epithelial cell | 4 studies | 37% ± 15% | |
Mueller cell | 4 studies | 35% ± 13% | |
OFF-bipolar cell | 4 studies | 56% ± 22% | |
macrophage | 3 studies | 31% ± 12% | |
differentiation-committed oligodendrocyte precursor | 3 studies | 63% ± 1% | |
GABAergic interneuron | 3 studies | 81% ± 9% | |
GABAergic amacrine cell | 3 studies | 66% ± 13% | |
ON-bipolar cell | 3 studies | 63% ± 5% | |
glycinergic amacrine cell | 3 studies | 42% ± 13% | |
retina horizontal cell | 3 studies | 28% ± 11% | |
pancreatic A cell | 3 studies | 52% ± 22% | |
ependymal cell | 3 studies | 43% ± 26% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 11224.24 | 2636 / 2642 | 98% | 150.05 | 690 / 705 |
prostate | 78% | 2288.33 | 190 / 245 | 74% | 11.97 | 369 / 502 |
ovary | 99% | 4125.18 | 179 / 180 | 30% | 3.30 | 128 / 430 |
bladder | 90% | 5427.76 | 19 / 21 | 18% | 4.74 | 89 / 504 |
esophagus | 62% | 2275.72 | 897 / 1445 | 44% | 12.32 | 80 / 183 |
adrenal gland | 31% | 766.14 | 79 / 258 | 69% | 104.64 | 158 / 230 |
skin | 56% | 1083.70 | 1022 / 1809 | 31% | 4.85 | 144 / 472 |
uterus | 45% | 724.30 | 76 / 170 | 33% | 7.85 | 152 / 459 |
breast | 35% | 529.55 | 160 / 459 | 40% | 6.02 | 452 / 1118 |
pancreas | 2% | 22.70 | 5 / 328 | 65% | 12.10 | 116 / 178 |
tonsil | 0% | 0 | 0 / 0 | 47% | 10.70 | 21 / 45 |
lung | 6% | 63.74 | 35 / 578 | 39% | 9.88 | 447 / 1155 |
stomach | 32% | 1078.67 | 116 / 359 | 9% | 1.96 | 27 / 286 |
blood vessel | 38% | 1181.38 | 513 / 1335 | 0% | 0 | 0 / 0 |
kidney | 31% | 500.53 | 28 / 89 | 6% | 0.58 | 53 / 901 |
intestine | 30% | 409.31 | 285 / 966 | 7% | 1.45 | 35 / 527 |
adipose | 13% | 151.33 | 156 / 1204 | 0% | 0 | 0 / 0 |
thymus | 8% | 88.52 | 50 / 653 | 4% | 0.42 | 23 / 605 |
spleen | 9% | 98.26 | 21 / 241 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 6% | 0.62 | 5 / 80 |
liver | 0% | 0 | 0 / 226 | 5% | 1.60 | 21 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007219 | Biological process | Notch signaling pathway |
GO_0010976 | Biological process | positive regulation of neuron projection development |
GO_0010628 | Biological process | positive regulation of gene expression |
GO_0032289 | Biological process | central nervous system myelin formation |
GO_0007155 | Biological process | cell adhesion |
GO_0010765 | Biological process | positive regulation of sodium ion transport |
GO_0021549 | Biological process | cerebellum development |
GO_0007420 | Biological process | brain development |
GO_0010467 | Biological process | gene expression |
GO_0098609 | Biological process | cell-cell adhesion |
GO_0007626 | Biological process | locomotory behavior |
GO_0007411 | Biological process | axon guidance |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0042734 | Cellular component | presynaptic membrane |
GO_0045211 | Cellular component | postsynaptic membrane |
GO_0098552 | Cellular component | side of membrane |
GO_0030424 | Cellular component | axon |
GO_0098632 | Molecular function | cell-cell adhesion mediator activity |
GO_0030246 | Molecular function | carbohydrate binding |
GO_0005515 | Molecular function | protein binding |
Gene name | CNTN1 |
Protein name | Contactin 1 Contactin-1 (Glycoprotein gp135) (Neural cell surface protein F3) |
Synonyms | |
Description | FUNCTION: Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth (By similarity). . |
Accessions | ENST00000552248.5 ENST00000551424.5 ENST00000347616.5 [Q12860-1] ENST00000547702.5 [Q12860-3] F8VUI8 ENST00000552913.5 Q12860 ENST00000548005.5 ENST00000548481.1 F8VUI9 ENST00000348761.2 [Q12860-2] H0YIJ1 ENST00000547849.6 [Q12860-3] ENST00000551295.7 [Q12860-1] F8VX96 F8VQW3 |