CNN1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CNN1 at tissue level.

III. Associated gene sets

GO_0006940Biological processregulation of smooth muscle contraction
GO_1904706Biological processnegative regulation of vascular associated smooth muscle cell proliferation
GO_0007015Biological processactin filament organization
GO_0031032Biological processactomyosin structure organization
GO_0015629Cellular componentactin cytoskeleton
GO_0005856Cellular componentcytoskeleton
GO_0005925Cellular componentfocal adhesion
GO_0005516Molecular functioncalmodulin binding
GO_0051015Molecular functionactin filament binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCNN1
Protein nameCalponin
Calponin-1 (Basic calponin) (Calponin H1, smooth muscle)
Transgelin
Calponin 1
Synonyms
DescriptionFUNCTION: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity). .

FUNCTION: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. .

FUNCTION: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. .

AccessionsK7ESJ2
ENST00000588935.1
ENST00000592923.5
ENST00000252456.7 [P51911-1]
K7ERK4
ENST00000587087.5
ENST00000585869.1
K7ER02
P51911
K7EQ72
K7ENC5
ENST00000592338.5
ENST00000586577.1
ENST00000586059.5
ENST00000535659.6
K7ERM8
B7Z7E1