CNIH2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CNIH2 at tissue level.

III. Associated gene sets

GO_0016192Biological processvesicle-mediated transport
GO_2000311Biological processregulation of AMPA receptor activity
GO_0033116Cellular componentendoplasmic reticulum-Golgi intermediate compartment membrane
GO_0012507Cellular componentER to Golgi transport vesicle membrane
GO_0045211Cellular componentpostsynaptic membrane
GO_0045202Cellular componentsynapse
GO_0032281Cellular componentAMPA glutamate receptor complex
GO_0043197Cellular componentdendritic spine
GO_0014069Cellular componentpostsynaptic density
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0043198Cellular componentdendritic shaft
GO_0030425Cellular componentdendrite
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCNIH2
Protein nameCornichon family AMPA receptor auxiliary protein 2
Protein cornichon homolog 2 (Cornichon family AMPA receptor auxiliary protein 2)
Protein cornichon homolog 2 (CNIH-2) (Cornichon family AMPA receptor auxiliary protein 2) (Cornichon-like protein)
SynonymsCNIL
DescriptionFUNCTION: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors. .

AccessionsE9PJQ8
E9PIT8
ENST00000528063.5
ENST00000534826.5
ENST00000311445.7
Q6PI25
ENST00000528852.5
E9PS15