CNGA1 | OmnibusX

Name	Number of supported studies	Average coverage
retinal rod cell	9 studies	74% ± 13%	Explore

Name	Number of supported studies	Average coverage
eye	6 studies	46% ± 18%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	89%	150.07	217 / 245	98%	5.52	493 / 502
liver	97%	656.08	220 / 226	83%	8.49	339 / 406
pancreas	83%	81.39	273 / 328	75%	3.72	134 / 178
bladder	76%	315.19	16 / 21	78%	9.96	395 / 504
esophagus	69%	192.94	1002 / 1445	80%	3.62	146 / 183
kidney	100%	203.66	89 / 89	39%	1.46	352 / 901
stomach	78%	99.87	281 / 359	60%	1.88	173 / 286
thymus	91%	179.42	597 / 653	44%	1.07	265 / 605
breast	93%	227.87	429 / 459	37%	1.39	409 / 1118
intestine	56%	157.38	539 / 966	72%	2.59	381 / 527
ureter	0%	0	0 / 0	100%	22.81	1 / 1
spleen	95%	327.06	230 / 241	0%	0	0 / 0
adipose	91%	279.81	1098 / 1204	0%	0	0 / 0
uterus	32%	32.55	55 / 170	55%	3.02	252 / 459
skin	72%	270.26	1304 / 1809	8%	0.20	38 / 472
muscle	67%	71.17	537 / 803	0%	0	0 / 0
lung	10%	6.72	56 / 578	43%	1.48	500 / 1155
adrenal gland	38%	43.90	97 / 258	4%	0.09	9 / 230
tonsil	0%	0	0 / 0	40%	0.92	18 / 45
ovary	2%	2.09	3 / 180	32%	1.04	137 / 430
heart	30%	27.65	256 / 861	0%	0	0 / 0
brain	15%	9.35	395 / 2642	3%	0.04	22 / 705
blood vessel	15%	13.49	204 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	4%	1.07	3 / 80
peripheral blood	2%	1.68	23 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0007601	Biological process	visual perception
GO_0006814	Biological process	sodium ion transport
GO_0098655	Biological process	monoatomic cation transmembrane transport
GO_0006816	Biological process	calcium ion transport
GO_0035725	Biological process	sodium ion transmembrane transport
GO_0070588	Biological process	calcium ion transmembrane transport
GO_0042622	Cellular component	photoreceptor outer segment membrane
GO_0017071	Cellular component	intracellular cyclic nucleotide activated cation channel complex
GO_0005886	Cellular component	plasma membrane
GO_0120200	Cellular component	rod photoreceptor outer segment
GO_0044877	Molecular function	protein-containing complex binding
GO_0005272	Molecular function	sodium channel activity
GO_0005222	Molecular function	intracellularly cAMP-activated cation channel activity
GO_0005223	Molecular function	intracellularly cGMP-activated cation channel activity
GO_0030552	Molecular function	cAMP binding
GO_0005515	Molecular function	protein binding
GO_0005262	Molecular function	calcium channel activity
GO_0030553	Molecular function	cGMP binding

Gene name	CNGA1
Protein name	cGMP-gated cation channel alpha-1 (Cyclic nucleotide-gated cation channel 1) (Cyclic nucleotide-gated channel alpha-1) (CNG channel alpha-1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel, photoreceptor) (Rod photoreceptor cGMP-gated channel subunit alpha) Cyclic nucleotide gated channel subunit alpha 1
Synonyms	CNCG CNCG1
Description	FUNCTION: Subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway. When light hits rod photoreceptors, cGMP concentrations decrease causing rapid closure of CNGA1/CNGB1 channels and, therefore, hyperpolarization of the membrane potential. .
Accessions	ENST00000402813.9 ENST00000504722.6 ENST00000514170.7 D6R978 ENST00000513178.2 ENST00000514520.6 D6RCF1 ENST00000420489.7 P29973

CNGA1 report