Insufficient scRNA-seq data for expression of CMA1 at tissue level.
Tissue | GTEx Coverage  | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 80% | 129.80 | 366 / 459 | 45% | 2.05 | 499 / 1118 |
| esophagus | 72% | 160.19 | 1037 / 1445 | 13% | 0.38 | 23 / 183 |
| bladder | 62% | 115.71 | 13 / 21 | 22% | 1.73 | 112 / 504 |
| adipose | 80% | 242.05 | 967 / 1204 | 0% | 0 | 0 / 0 |
| skin | 68% | 197.51 | 1235 / 1809 | 10% | 0.42 | 48 / 472 |
| intestine | 63% | 88.33 | 607 / 966 | 14% | 0.44 | 76 / 527 |
| prostate | 36% | 35.07 | 88 / 245 | 30% | 0.77 | 150 / 502 |
| stomach | 41% | 43.60 | 146 / 359 | 14% | 0.47 | 39 / 286 |
| pancreas | 5% | 2.50 | 18 / 328 | 34% | 1.67 | 61 / 178 |
| lung | 21% | 14.80 | 123 / 578 | 17% | 0.56 | 200 / 1155 |
| uterus | 26% | 22.88 | 45 / 170 | 11% | 0.81 | 52 / 459 |
| thymus | 7% | 3.89 | 48 / 653 | 21% | 0.74 | 130 / 605 |
| kidney | 8% | 6.38 | 7 / 89 | 20% | 0.88 | 184 / 901 |
| heart | 25% | 14.17 | 212 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 24% | 0.55 | 7 / 29 |
| liver | 11% | 5.06 | 24 / 226 | 10% | 0.75 | 41 / 406 |
| blood vessel | 18% | 14.57 | 234 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 16% | 9.50 | 129 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 16% | 0.65 | 7 / 45 |
| peripheral blood | 12% | 9.85 | 112 / 929 | 0% | 0 | 0 / 0 |
| ovary | 6% | 3.13 | 10 / 180 | 3% | 0.11 | 11 / 430 |
| spleen | 7% | 6.56 | 16 / 241 | 0% | 0 | 0 / 0 |
| adrenal gland | 0% | 0 | 0 / 258 | 4% | 0.29 | 9 / 230 |
| brain | 0% | 0 | 0 / 2642 | 0% | 0.00 | 2 / 705 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0071333 | Biological process | cellular response to glucose stimulus |
| GO_0045766 | Biological process | positive regulation of angiogenesis |
| GO_0022617 | Biological process | extracellular matrix disassembly |
| GO_0050727 | Biological process | regulation of inflammatory response |
| GO_0002003 | Biological process | angiotensin maturation |
| GO_0030163 | Biological process | protein catabolic process |
| GO_0034769 | Biological process | basement membrane disassembly |
| GO_0006518 | Biological process | peptide metabolic process |
| GO_0140447 | Biological process | cytokine precursor processing |
| GO_0030901 | Biological process | midbrain development |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0036464 | Cellular component | cytoplasmic ribonucleoprotein granule |
| GO_0062023 | Cellular component | collagen-containing extracellular matrix |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0030141 | Cellular component | secretory granule |
| GO_0004175 | Molecular function | endopeptidase activity |
| GO_0042277 | Molecular function | peptide binding |
| GO_0008236 | Molecular function | serine-type peptidase activity |
| GO_0004252 | Molecular function | serine-type endopeptidase activity |
| Gene name | CMA1 |
| Protein name | Chymase 1 preproprotein transcript E Chymase (EC 3.4.21.39) (Alpha-chymase) (Mast cell protease I) Chymase 1 preproprotein transcript I |
| Synonyms | CYM CYH |
| Description | FUNCTION: Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. |
| Accessions | Q4FEB3 ENST00000206446.4 [P23946-2] P23946 ENST00000250378.7 [P23946-1] Q4FEB5 |
