Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| endothelial cell | 5 studies | 20% ± 4% | |
| epithelial cell | 4 studies | 33% ± 12% | |
| CD4-positive, alpha-beta T cell | 3 studies | 18% ± 2% | |
| classical monocyte | 3 studies | 23% ± 5% | |
| conventional dendritic cell | 3 studies | 25% ± 8% | |
| non-classical monocyte | 3 studies | 25% ± 5% | |
| B cell | 3 studies | 20% ± 2% | |
| natural killer cell | 3 studies | 19% ± 2% | |
| CD8-positive, alpha-beta T cell | 3 studies | 18% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| bladder | 100% | 4241.14 | 21 / 21 | 100% | 8.64 | 504 / 504 |
| esophagus | 100% | 4024.72 | 1445 / 1445 | 100% | 6.90 | 183 / 183 |
| prostate | 100% | 5496.35 | 245 / 245 | 100% | 10.32 | 502 / 502 |
| stomach | 100% | 3386.20 | 359 / 359 | 100% | 6.33 | 286 / 286 |
| thymus | 100% | 5745.17 | 653 / 653 | 100% | 10.29 | 605 / 605 |
| uterus | 100% | 4984.78 | 170 / 170 | 100% | 9.19 | 459 / 459 |
| intestine | 100% | 4541.46 | 966 / 966 | 100% | 7.11 | 526 / 527 |
| skin | 100% | 3955.35 | 1809 / 1809 | 100% | 8.83 | 471 / 472 |
| ovary | 100% | 5097.32 | 180 / 180 | 100% | 7.36 | 429 / 430 |
| lung | 100% | 4604.38 | 578 / 578 | 100% | 7.69 | 1152 / 1155 |
| breast | 100% | 4207.37 | 459 / 459 | 100% | 7.90 | 1114 / 1118 |
| brain | 100% | 2725.58 | 2631 / 2642 | 100% | 7.59 | 705 / 705 |
| kidney | 100% | 3753.39 | 89 / 89 | 99% | 7.62 | 892 / 901 |
| pancreas | 100% | 2019.64 | 328 / 328 | 99% | 8.78 | 176 / 178 |
| adrenal gland | 100% | 3418.90 | 258 / 258 | 98% | 7.93 | 226 / 230 |
| liver | 100% | 2250.83 | 226 / 226 | 95% | 4.41 | 386 / 406 |
| adipose | 100% | 3912.04 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 3915.28 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 10.34 | 29 / 29 |
| muscle | 100% | 2713.53 | 803 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 100% | 5885.33 | 929 / 929 | 0% | 0 | 0 / 0 |
| spleen | 100% | 5973.70 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 6.71 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.67 | 1 / 1 |
| heart | 99% | 2500.78 | 854 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 6.57 | 79 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0043484 | Biological process | regulation of RNA splicing |
| GO_0006468 | Biological process | protein phosphorylation |
| GO_0045111 | Cellular component | intermediate filament cytoskeleton |
| GO_0016607 | Cellular component | nuclear speck |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0001669 | Cellular component | acrosomal vesicle |
| GO_0016020 | Cellular component | membrane |
| GO_0005634 | Cellular component | nucleus |
| GO_0004713 | Molecular function | protein tyrosine kinase activity |
| GO_0004674 | Molecular function | protein serine/threonine kinase activity |
| GO_0004712 | Molecular function | protein serine/threonine/tyrosine kinase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0106310 | Molecular function | protein serine kinase activity |
| GO_0005524 | Molecular function | ATP binding |
| GO_0003723 | Molecular function | RNA binding |
| Gene name | CLK3 |
| Protein name | dual-specificity kinase (EC 2.7.12.1) Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3) CDC like kinase 3 |
| Synonyms | hCG_1739025 |
| Description | FUNCTION: Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Phosphorylates SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells. . |
| Accessions | B3KTV2 ENST00000395066.9 [P49761-1] ENST00000568139.6 ENST00000563297.5 ENST00000566926.1 P49761 H3BTW9 ENST00000562670.5 H3BRE4 ENST00000345005.8 [P49761-1] H3BRT8 H3BRK0 H3BV35 ENST00000568488.6 ENST00000566126.5 ENST00000483723.5 [P49761-2] H3BNQ5 H3BQR7 H3BRW2 ENST00000563842.5 H3BVF8 H3BQG1 H3BNC8 ENST00000563418.2 ENST00000562389.5 ENST00000564096.1 ENST00000569063.5 ENST00000564468.5 H3BUL5 |
