CLEC4G report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CLEC4G at tissue level.

III. Associated gene sets

GO_0046642Biological processnegative regulation of alpha-beta T cell proliferation
GO_0044419Biological processbiological process involved in interspecies interaction between organisms
GO_1903902Biological processpositive regulation of viral life cycle
GO_0006955Biological processimmune response
GO_0046718Biological processsymbiont entry into host cell
GO_0002710Biological processnegative regulation of T cell mediated immunity
GO_0033088Biological processnegative regulation of immature T cell proliferation in thymus
GO_0002456Biological processT cell mediated immunity
GO_0033080Biological processimmature T cell proliferation in thymus
GO_0046633Biological processalpha-beta T cell proliferation
GO_0009897Cellular componentexternal side of plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0120274Molecular functionvirus coreceptor activity
GO_0030247Molecular functionpolysaccharide binding
GO_0005537Molecular functionD-mannose binding
GO_0030246Molecular functioncarbohydrate binding
GO_0001618Molecular functionvirus receptor activity
GO_0097367Molecular functioncarbohydrate derivative binding
GO_0140081Molecular functionglycosylated region protein binding
GO_0070061Molecular functionfructose binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCLEC4G
Protein nameC-type lectin domain family 4 member G
CLEC4G protein
C-type lectin domain family 4 member G (Liver and lymph node sinusoidal endothelial cell C-type lectin) (LSECtin)
SynonymsUNQ431/PRO792
DescriptionFUNCTION: Binds mannose, N-acetylglucosamine (GlcNAc) and fucose, but not galactose, in a Ca(2+)-dependent manner, in vitro. .; FUNCTION: (Microbial infection) Acts as a receptor for Japanese encephalitis virus. .; FUNCTION: (Microbial infection) Acts as a receptor for Ebolavirus. .; FUNCTION: (Microbial infection) Acts as a receptor for SARS-CoV. .; FUNCTION: (Microbial infection) Acts as a receptor for Lassa virus and Lymphocytic choriomeningitis virus glycoprotein . .

AccessionsA0A7I2V4C7
M0R277
Q6UXB4
A0A7I2V4U5
ENST00000678118.1
ENST00000328853.11
ENST00000599020.1
B7ZKQ2
ENST00000676742.1