CLCN6 | OmnibusX

Name	Number of supported studies	Average coverage
endothelial cell	4 studies	25% ± 9%	Explore
microglial cell	3 studies	24% ± 1%	Explore
retinal ganglion cell	3 studies	42% ± 20%	Explore
GABAergic neuron	3 studies	32% ± 11%	Explore
glutamatergic neuron	3 studies	38% ± 15%	Explore
oligodendrocyte precursor cell	3 studies	26% ± 1%	Explore
macrophage	3 studies	24% ± 6%	Explore
astrocyte	3 studies	22% ± 5%	Explore

Name	Number of supported studies	Average coverage
brain	5 studies	25% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	3591.86	245 / 245	100%	9.25	502 / 502
brain	100%	4670.27	2640 / 2642	100%	33.11	705 / 705
skin	100%	2404.79	1808 / 1809	100%	14.60	471 / 472
thymus	100%	4230.90	653 / 653	99%	9.93	601 / 605
esophagus	100%	2713.04	1443 / 1445	99%	9.53	182 / 183
kidney	100%	2827.80	89 / 89	99%	10.82	892 / 901
uterus	100%	4273.94	170 / 170	98%	7.64	452 / 459
adrenal gland	100%	3747.17	258 / 258	98%	12.04	226 / 230
bladder	100%	3086.86	21 / 21	98%	6.40	494 / 504
lung	100%	3883.02	578 / 578	98%	8.06	1132 / 1155
stomach	100%	2313.88	359 / 359	98%	6.73	280 / 286
breast	100%	3456.33	459 / 459	98%	7.44	1093 / 1118
intestine	100%	3363.24	966 / 966	97%	6.08	509 / 527
ovary	100%	4706.53	180 / 180	96%	9.01	414 / 430
pancreas	98%	1422.86	322 / 328	98%	8.51	174 / 178
liver	100%	1895.27	226 / 226	87%	4.57	355 / 406
adipose	100%	3414.73	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	8.62	29 / 29
spleen	100%	3206.70	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	3.64	1 / 1
blood vessel	100%	2950.62	1334 / 1335	0%	0	0 / 0
muscle	99%	1836.95	798 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	99%	15.22	79 / 80
tonsil	0%	0	0 / 0	98%	5.67	44 / 45
heart	98%	2259.31	840 / 861	0%	0	0 / 0
peripheral blood	63%	1120.00	582 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0007165	Biological process	signal transduction
GO_0034220	Biological process	monoatomic ion transmembrane transport
GO_0009612	Biological process	response to mechanical stimulus
GO_1902476	Biological process	chloride transmembrane transport
GO_0006884	Biological process	cell volume homeostasis
GO_0006821	Biological process	chloride transport
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0010008	Cellular component	endosome membrane
GO_0031902	Cellular component	late endosome membrane
GO_0005765	Cellular component	lysosomal membrane
GO_0016020	Cellular component	membrane
GO_0015297	Molecular function	antiporter activity
GO_0005247	Molecular function	voltage-gated chloride channel activity
GO_0015108	Molecular function	chloride transmembrane transporter activity
GO_0005524	Molecular function	ATP binding

Gene name	CLCN6
Protein name	Chloride voltage-gated channel 6 CLCN6 H(+)/Cl(-) exchange transporter 6 (Chloride channel protein 6) (ClC-6) (Chloride transport protein 6)
Synonyms	KIAA0046
Description	FUNCTION: Voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the late endosome lumen. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The presence of conserved gating glutamate residues is typical for family members that function as antiporters. .
Accessions	ENST00000312413.10 [P51797-6] Q8IZX0 P51797 ENST00000400892.3 ENST00000376496.4 [P51797-5] ENST00000346436.11 [P51797-1] A0A3B3IRY0

CLCN6 report