CLC report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CLC at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CLC at tissue level.

III. Associated gene sets

GO_0002667Biological processregulation of T cell anergy
GO_0046006Biological processregulation of activated T cell proliferation
GO_0070231Biological processT cell apoptotic process
GO_0002724Biological processregulation of T cell cytokine production
GO_0005829Cellular componentcytosol
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0004622Molecular functionlysophospholipase activity
GO_0097153Molecular functioncysteine-type endopeptidase activity involved in apoptotic process
GO_0030246Molecular functioncarbohydrate binding
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCLC
Protein nameGalectin-10 (Gal-10) (Charcot-Leyden crystal protein) (CLC) (Eosinophil lysophospholipase) (Lysolecithin acylhydrolase)
SynonymsLGALS10A
LGALS10
DescriptionFUNCTION: Regulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg). .

AccessionsENST00000221804.5
Q05315