Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 7 studies | 26% ± 9% | |
retinal cone cell | 4 studies | 27% ± 8% | |
oligodendrocyte precursor cell | 4 studies | 26% ± 9% | |
astrocyte | 4 studies | 29% ± 13% | |
epithelial cell | 3 studies | 29% ± 2% | |
ciliated cell | 3 studies | 21% ± 3% | |
GABAergic neuron | 3 studies | 24% ± 2% | |
glutamatergic neuron | 3 studies | 24% ± 4% | |
goblet cell | 3 studies | 21% ± 5% | |
neuron | 3 studies | 19% ± 5% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 4 studies | 27% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1992.94 | 1445 / 1445 | 100% | 33.50 | 183 / 183 |
prostate | 100% | 1889.31 | 245 / 245 | 100% | 29.25 | 502 / 502 |
breast | 100% | 2000.37 | 459 / 459 | 100% | 26.67 | 1114 / 1118 |
brain | 100% | 1518.67 | 2637 / 2642 | 100% | 24.76 | 702 / 705 |
intestine | 100% | 2285.10 | 966 / 966 | 99% | 19.52 | 523 / 527 |
lung | 99% | 1294.07 | 574 / 578 | 100% | 24.71 | 1151 / 1155 |
stomach | 100% | 1781.85 | 359 / 359 | 99% | 22.11 | 282 / 286 |
ovary | 100% | 1800.32 | 180 / 180 | 97% | 12.52 | 417 / 430 |
bladder | 100% | 1897.71 | 21 / 21 | 97% | 14.62 | 487 / 504 |
pancreas | 99% | 875.55 | 324 / 328 | 98% | 12.81 | 174 / 178 |
thymus | 100% | 1356.39 | 652 / 653 | 96% | 11.22 | 579 / 605 |
skin | 100% | 1892.28 | 1808 / 1809 | 95% | 23.38 | 448 / 472 |
uterus | 100% | 1982.55 | 170 / 170 | 92% | 13.05 | 423 / 459 |
liver | 100% | 825.76 | 225 / 226 | 91% | 14.21 | 369 / 406 |
kidney | 99% | 672.90 | 88 / 89 | 88% | 11.29 | 789 / 901 |
adrenal gland | 100% | 5251.79 | 258 / 258 | 76% | 13.58 | 174 / 230 |
adipose | 100% | 1834.59 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 971.96 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 18.75 | 45 / 45 |
blood vessel | 100% | 2035.79 | 1334 / 1335 | 0% | 0 | 0 / 0 |
muscle | 97% | 652.11 | 777 / 803 | 0% | 0 | 0 / 0 |
heart | 96% | 741.21 | 829 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 86% | 13.68 | 69 / 80 |
lymph node | 0% | 0 | 0 / 0 | 59% | 4.17 | 17 / 29 |
peripheral blood | 43% | 328.34 | 398 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0060271 | Biological process | cilium assembly |
GO_0007165 | Biological process | signal transduction |
GO_0035721 | Biological process | intraciliary retrograde transport |
GO_0035556 | Biological process | intracellular signal transduction |
GO_0006468 | Biological process | protein phosphorylation |
GO_0035720 | Biological process | intraciliary anterograde transport |
GO_0042073 | Biological process | intraciliary transport |
GO_0001650 | Cellular component | fibrillar center |
GO_0097542 | Cellular component | ciliary tip |
GO_0005929 | Cellular component | cilium |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0097546 | Cellular component | ciliary base |
GO_0036064 | Cellular component | ciliary basal body |
GO_0005634 | Cellular component | nucleus |
GO_0106310 | Molecular function | protein serine kinase activity |
GO_0004674 | Molecular function | protein serine/threonine kinase activity |
GO_0000287 | Molecular function | magnesium ion binding |
GO_0004672 | Molecular function | protein kinase activity |
GO_0005524 | Molecular function | ATP binding |
GO_0005515 | Molecular function | protein binding |
Gene name | CILK1 |
Protein name | Ciliogenesis associated kinase 1 Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Ciliogenesis associated kinase 1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK) |
Synonyms | KIAA0936 ICK |
Description | FUNCTION: Required for ciliogenesis . Phosphorylates KIF3A (By similarity). Involved in the control of ciliary length . Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (By similarity). May play a key role in the development of multiple organ systems and particularly in cardiac development (By similarity). Regulates intraflagellar transport (IFT) speed and negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner and this regulation requires its kinase activity (By similarity). . |
Accessions | ENST00000676107.1 [Q9UPZ9-1] ENST00000356971.3 [Q9UPZ9-1] Q9UPZ9 ENST00000350082.10 A0A7I2PIU1 |