CIAO3 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CIAO3 at tissue level.

III. Associated gene sets

GO_0032364Biological processintracellular oxygen homeostasis
GO_0002244Biological processhematopoietic progenitor cell differentiation
GO_0010468Biological processregulation of gene expression
GO_0016226Biological processiron-sulfur cluster assembly
GO_0001666Biological processresponse to hypoxia
GO_0097361Cellular componentcytosolic [4Fe-4S] assembly targeting complex
GO_0005515Molecular functionprotein binding
GO_0051539Molecular function4 iron, 4 sulfur cluster binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameCIAO3
Protein nameCytosolic iron-sulfur assembly component 3 (cDNA FLJ59849, highly similar to Homo sapiens nuclear prelamin A recognition factor-like (NARFL), mRNA)
Cytosolic iron-sulfur assembly component 3
Cytosolic iron-sulfur assembly component 3 (Cytosolic Fe-S cluster assembly factor NARFL) (Iron-only hydrogenase-like protein 1) (IOP1) (Nuclear prelamin A recognition factor-like protein) (Protein related to Narf)
SynonymsPRN
NARFL
DescriptionFUNCTION: Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect. .

AccessionsENST00000562421.5
ENST00000540986.5 [Q9H6Q4-3]
ENST00000251588.7 [Q9H6Q4-1]
ENST00000567403.5
H3BUF3
I3L2A3
ENST00000568545.5 [Q9H6Q4-3]
H3BQ03
ENST00000570066.1
H3BSH2
H3BPX8
H3BSJ7
ENST00000565425.5
ENST00000570289.5
ENST00000565065.5
ENST00000566614.5
B4DEE7
Q9H6Q4