I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| extravillous trophoblast | 3 studies | 80% ± 6% | |
| placental villous trophoblast | 3 studies | 85% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| extravillous trophoblast | 3 studies | 80% ± 6% | |
| placental villous trophoblast | 3 studies | 85% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| placenta | 3 studies | 77% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 75% | 110.55 | 184 / 245 | 29% | 9.70 | 146 / 502 |
| adrenal gland | 72% | 125.91 | 187 / 258 | 31% | 7.91 | 71 / 230 |
| kidney | 88% | 94.67 | 78 / 89 | 4% | 0.85 | 34 / 901 |
| liver | 58% | 35.48 | 130 / 226 | 10% | 0.52 | 40 / 406 |
| pancreas | 57% | 24.96 | 187 / 328 | 6% | 0.48 | 10 / 178 |
| stomach | 52% | 157.39 | 186 / 359 | 6% | 2.33 | 17 / 286 |
| breast | 27% | 5.37 | 125 / 459 | 29% | 46.42 | 319 / 1118 |
| heart | 55% | 29.72 | 473 / 861 | 0% | 0 | 0 / 0 |
| skin | 49% | 57.73 | 893 / 1809 | 1% | 0.01 | 3 / 472 |
| muscle | 49% | 73.17 | 396 / 803 | 0% | 0 | 0 / 0 |
| ovary | 48% | 15.29 | 86 / 180 | 1% | 0.02 | 4 / 430 |
| lung | 39% | 10.82 | 223 / 578 | 9% | 11.02 | 100 / 1155 |
| uterus | 36% | 10.34 | 61 / 170 | 8% | 9.34 | 36 / 459 |
| spleen | 41% | 16.52 | 99 / 241 | 0% | 0 | 0 / 0 |
| brain | 38% | 13.19 | 1011 / 2642 | 1% | 0.05 | 10 / 705 |
| esophagus | 31% | 28.03 | 452 / 1445 | 8% | 0.79 | 14 / 183 |
| thymus | 34% | 24.47 | 224 / 653 | 2% | 0.09 | 13 / 605 |
| intestine | 31% | 10.49 | 296 / 966 | 3% | 0.32 | 18 / 527 |
| adipose | 29% | 17.26 | 349 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 23% | 30.04 | 304 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 21% | 5.88 | 194 / 929 | 0% | 0 | 0 / 0 |
| bladder | 14% | 2.10 | 3 / 21 | 6% | 4.38 | 31 / 504 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.19 | 1 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 1.55 | 1 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0035265 | Biological process | organ growth |
| GO_0046884 | Biological process | follicle-stimulating hormone secretion |
| GO_0006590 | Biological process | thyroid hormone generation |
| GO_0010469 | Biological process | regulation of signaling receptor activity |
| GO_0030878 | Biological process | thyroid gland development |
| GO_0046621 | Biological process | negative regulation of organ growth |
| GO_0042699 | Biological process | follicle-stimulating hormone signaling pathway |
| GO_0010893 | Biological process | positive regulation of steroid biosynthetic process |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0030335 | Biological process | positive regulation of cell migration |
| GO_0032275 | Biological process | luteinizing hormone secretion |
| GO_0009755 | Biological process | hormone-mediated signaling pathway |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0061696 | Cellular component | pituitary gonadotropin complex |
| GO_0005796 | Cellular component | Golgi lumen |
| GO_0016914 | Cellular component | follicle-stimulating hormone complex |
| GO_0016913 | Molecular function | follicle-stimulating hormone activity |
| GO_0005179 | Molecular function | hormone activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CGA |
| Protein name | Glycoprotein hormones alpha chain Glycoprotein hormones alpha chain (Anterior pituitary glycoprotein hormones common subunit alpha) (Choriogonadotropin alpha chain) (Chorionic gonadotrophin subunit alpha) (CG-alpha) (Follicle-stimulating hormone alpha chain) (FSH-alpha) (Follitropin alpha chain) (Luteinizing hormone alpha chain) (LSH-alpha) (Lutropin alpha chain) (Thyroid-stimulating hormone alpha chain) (TSH-alpha) (Thyrotropin alpha chain) |
| Synonyms | hCG_33165 FSHA GPA1 |
| Description | FUNCTION: Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. . FUNCTION: Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. . FUNCTION: Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. . FUNCTION: Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. . FUNCTION: Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. . FUNCTION: Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. . FUNCTION: Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. . FUNCTION: Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. . |
| Accessions | A0A0D9SFJ6 P01215 Q6I9S8 ENST00000369582.6 ENST00000610310.3 A0A0R4J2F0 ENST00000627148.3 C0KRQ8 A0A0D9SGA7 ENST00000630630.2 Q96QJ4 ENST00000625577.1 A0A087WYZ4 |
