CFAP58 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CFAP58 at tissue level.

III. Associated gene sets

GO_0060271Biological processcilium assembly
GO_0007288Biological processsperm axoneme assembly
GO_0120316Biological processsperm flagellum assembly
GO_0030317Biological processflagellated sperm motility
GO_0007219Biological processNotch signaling pathway
GO_0120317Biological processsperm mitochondrial sheath assembly
GO_0120229Biological processprotein localization to motile cilium
GO_0005813Cellular componentcentrosome
GO_0005615Cellular componentextracellular space
GO_0097225Cellular componentsperm midpiece
GO_0005856Cellular componentcytoskeleton
GO_0036126Cellular componentsperm flagellum
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCFAP58
Protein nameCilia- and flagella-associated protein 58 (Coiled-coil domain-containing protein 147)
Cilia and flagella associated protein 58
SynonymsC10orf80
CCDC147
DescriptionFUNCTION: Has an essential role in the assembly and organization of the sperm flagellar axoneme . Required for the elongation of the primary cilium and sperm flagellar midpiece via modulation of the Notch signaling pathway (By similarity). .

AccessionsQ9H4Y4
ENST00000369704.8
ENST00000369703.1
Q5T655