CFAP45 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CFAP45 at tissue level.

III. Associated gene sets

GO_0090660Biological processcerebrospinal fluid circulation
GO_0060296Biological processregulation of cilium beat frequency involved in ciliary motility
GO_0030317Biological processflagellated sperm motility
GO_0060287Biological processepithelial cilium movement involved in determination of left/right asymmetry
GO_0061966Biological processestablishment of left/right asymmetry
GO_0005930Cellular componentaxoneme
GO_0005879Cellular componentaxonemal microtubule
GO_0005654Cellular componentnucleoplasm
GO_0005576Cellular componentextracellular region
GO_0097729Cellular component9+2 motile cilium
GO_0160112Cellular componentaxonemal B tubule inner sheath
GO_0097728Cellular component9+0 motile cilium
GO_0005634Cellular componentnucleus
GO_0016208Molecular functionAMP binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCFAP45
Protein nameCilia- and flagella-associated protein 45 (Coiled-coil domain-containing protein 19) (Nasopharyngeal epithelium-specific protein 1)
Cilia- and flagella-associated protein 45
SynonymshCG_39740
CCDC19
NESG1
DescriptionFUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating . It is an AMP-binding protein that may facilitate dynein ATPase-dependent ciliary and flagellar beating via adenine nucleotide homeostasis. May function as a donor of AMP to AK8 and hence promote ADP production . .

AccessionsA0A087X182
ENST00000476696.5
Q9UL16
ENST00000426543.6 [Q9UL16-2]
A0A087WUV1
ENST00000368099.9 [Q9UL16-1]
ENST00000479940.2