Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 18 studies | 78% ± 19% | |
smooth muscle cell | 12 studies | 25% ± 7% | |
fibroblast | 10 studies | 28% ± 14% | |
pericyte | 8 studies | 23% ± 8% | |
epithelial cell of proximal tubule | 7 studies | 28% ± 12% | |
connective tissue cell | 7 studies | 26% ± 6% | |
kidney loop of Henle epithelial cell | 6 studies | 22% ± 4% | |
myofibroblast cell | 6 studies | 20% ± 4% | |
epithelial cell | 5 studies | 50% ± 18% | |
basal cell | 5 studies | 46% ± 17% | |
deuterosomal cell | 4 studies | 42% ± 10% | |
pancreatic A cell | 4 studies | 35% ± 8% | |
endothelial cell | 4 studies | 27% ± 9% | |
type B pancreatic cell | 3 studies | 36% ± 5% | |
kidney distal convoluted tubule epithelial cell | 3 studies | 31% ± 12% | |
mesothelial cell | 3 studies | 35% ± 24% | |
retinal ganglion cell | 3 studies | 68% ± 21% | |
abnormal cell | 3 studies | 21% ± 6% | |
club cell | 3 studies | 25% ± 6% | |
erythroblast | 3 studies | 28% ± 8% | |
pancreatic ductal cell | 3 studies | 41% ± 12% | |
goblet cell | 3 studies | 28% ± 8% | |
secretory cell | 3 studies | 33% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
adrenal gland | 100% | 2464.31 | 258 / 258 | 100% | 120.68 | 230 / 230 |
ovary | 100% | 2873.79 | 180 / 180 | 100% | 147.96 | 430 / 430 |
uterus | 100% | 3552.59 | 170 / 170 | 100% | 125.42 | 459 / 459 |
kidney | 100% | 3526.07 | 89 / 89 | 100% | 121.32 | 900 / 901 |
brain | 100% | 2993.41 | 2639 / 2642 | 100% | 141.82 | 705 / 705 |
thymus | 100% | 3699.07 | 653 / 653 | 100% | 137.39 | 604 / 605 |
prostate | 100% | 2822.36 | 245 / 245 | 100% | 98.29 | 501 / 502 |
lung | 100% | 2527.32 | 576 / 578 | 100% | 107.86 | 1155 / 1155 |
breast | 100% | 1914.10 | 459 / 459 | 100% | 152.95 | 1113 / 1118 |
esophagus | 100% | 2762.47 | 1445 / 1445 | 99% | 69.45 | 182 / 183 |
skin | 100% | 1788.30 | 1805 / 1809 | 100% | 72.05 | 470 / 472 |
bladder | 100% | 2428.43 | 21 / 21 | 99% | 93.52 | 498 / 504 |
intestine | 100% | 2494.69 | 964 / 966 | 98% | 80.46 | 518 / 527 |
stomach | 98% | 1595.30 | 351 / 359 | 98% | 69.77 | 280 / 286 |
pancreas | 94% | 854.97 | 309 / 328 | 99% | 91.01 | 176 / 178 |
liver | 91% | 834.10 | 205 / 226 | 96% | 54.46 | 391 / 406 |
eye | 0% | 0 | 0 / 0 | 100% | 65.35 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 55.93 | 29 / 29 |
tonsil | 0% | 0 | 0 / 0 | 100% | 87.41 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 74.94 | 1 / 1 |
blood vessel | 100% | 2736.80 | 1334 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 1749.31 | 1203 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 1078.49 | 240 / 241 | 0% | 0 | 0 / 0 |
heart | 93% | 1350.30 | 799 / 861 | 0% | 0 | 0 / 0 |
muscle | 92% | 700.62 | 735 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 74% | 612.15 | 690 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007283 | Biological process | spermatogenesis |
GO_0000278 | Biological process | mitotic cell cycle |
GO_0051028 | Biological process | mRNA transport |
GO_0006289 | Biological process | nucleotide-excision repair |
GO_0051301 | Biological process | cell division |
GO_0015031 | Biological process | protein transport |
GO_0007099 | Biological process | centriole replication |
GO_0032465 | Biological process | regulation of cytokinesis |
GO_0032391 | Cellular component | photoreceptor connecting cilium |
GO_0097729 | Cellular component | 9+2 motile cilium |
GO_0005813 | Cellular component | centrosome |
GO_0005654 | Cellular component | nucleoplasm |
GO_0070390 | Cellular component | transcription export complex 2 |
GO_0005814 | Cellular component | centriole |
GO_0044615 | Cellular component | nuclear pore nuclear basket |
GO_0005829 | Cellular component | cytosol |
GO_0071942 | Cellular component | XPC complex |
GO_0036064 | Cellular component | ciliary basal body |
GO_0045177 | Cellular component | apical part of cell |
GO_0005634 | Cellular component | nucleus |
GO_0031683 | Molecular function | G-protein beta/gamma-subunit complex binding |
GO_0032795 | Molecular function | heterotrimeric G-protein binding |
GO_0008017 | Molecular function | microtubule binding |
GO_0005509 | Molecular function | calcium ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | CETN2 |
Protein name | Centrin-2 (Caltractin isoform 1) |
Synonyms | CALT CEN2 |
Description | FUNCTION: Plays a fundamental role in microtubule organizing center structure and function. Required for centriole duplication and correct spindle formation. Has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CCP110.; FUNCTION: Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with RAD23B appears to stabilize XPC. In vitro, stimulates DNA binding of the XPC:RAD23B dimer.; FUNCTION: The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair.; FUNCTION: As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores. . |
Accessions | ENST00000709996.1 ENST00000370277.5 P41208 |