CEP162 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0060271Biological processcilium assembly
GO_0005814Cellular componentcentriole
GO_0005879Cellular componentaxonemal microtubule
GO_0005813Cellular componentcentrosome
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0034451Cellular componentcentriolar satellite
GO_0005819Cellular componentspindle
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCEP162
Protein nameCentrosomal protein of 162 kDa
Centrosomal protein of 162 kDa (Cep162) (Protein QN1 homolog)
SynonymsC6orf84
QN1
KIAA1009
DescriptionFUNCTION: Required to promote assembly of the transition zone in primary cilia. Acts by specifically recognizing and binding the axonemal microtubule. Localizes to the distal ends of centrioles before ciliogenesis and directly binds to axonemal microtubule, thereby promoting and restricting transition zone formation specifically at the cilia base. Required to mediate CEP290 association with microtubules. .

AccessionsENST00000403245.8 [Q5TB80-1]
ENST00000257766.8 [Q5TB80-2]
ENST00000617909.2 [Q5TB80-2]
Q5TB80
F6V2J0
ENST00000435955.1