CENPT | OmnibusX

Name	Number of supported studies	Average coverage
endothelial cell	3 studies	24% ± 6%	Explore
platelet	3 studies	20% ± 5%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CENPT at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3768.54	1445 / 1445	100%	11.86	183 / 183
skin	100%	5456.71	1809 / 1809	100%	13.73	472 / 472
uterus	100%	5221.32	170 / 170	100%	22.13	459 / 459
adrenal gland	100%	3330.36	258 / 258	100%	16.51	229 / 230
ovary	100%	4964.92	180 / 180	100%	12.19	428 / 430
intestine	100%	4371.13	966 / 966	99%	12.32	524 / 527
bladder	100%	4178.10	21 / 21	99%	18.45	501 / 504
prostate	100%	5472.68	245 / 245	99%	13.60	499 / 502
stomach	100%	3184.23	359 / 359	99%	10.52	284 / 286
pancreas	100%	3010.36	328 / 328	99%	15.17	176 / 178
lung	100%	3806.99	578 / 578	99%	11.90	1141 / 1155
kidney	100%	3530.03	89 / 89	98%	12.77	886 / 901
thymus	100%	4390.35	653 / 653	98%	11.46	594 / 605
brain	98%	3786.65	2590 / 2642	100%	22.94	705 / 705
liver	100%	2057.12	226 / 226	98%	8.98	397 / 406
breast	100%	4220.98	459 / 459	97%	9.93	1090 / 1118
adipose	100%	3830.11	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	18.46	29 / 29
spleen	100%	5654.84	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	22.38	1 / 1
blood vessel	100%	3604.52	1333 / 1335	0%	0	0 / 0
heart	99%	2011.67	852 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	99%	10.88	79 / 80
tonsil	0%	0	0 / 0	98%	13.90	44 / 45
muscle	96%	1459.09	772 / 803	0%	0	0 / 0
peripheral blood	89%	1654.16	826 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0051301	Biological process	cell division
GO_0000278	Biological process	mitotic cell cycle
GO_0051276	Biological process	chromosome organization
GO_0007059	Biological process	chromosome segregation
GO_0051382	Biological process	kinetochore assembly
GO_0000775	Cellular component	chromosome, centromeric region
GO_0000776	Cellular component	kinetochore
GO_0005634	Cellular component	nucleus
GO_0005829	Cellular component	cytosol
GO_0005654	Cellular component	nucleoplasm
GO_0016604	Cellular component	nuclear body
GO_0000939	Cellular component	inner kinetochore
GO_0046982	Molecular function	protein heterodimerization activity
GO_0003677	Molecular function	DNA binding
GO_0005515	Molecular function	protein binding

Gene name	CENPT
Protein name	Centromere protein T (CENP-T) (Interphase centromere complex protein 22) Centromere protein T
Synonyms	C16orf56 ICEN22
Description	FUNCTION: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPT has a fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most further proteins binding downstream. Required for normal chromosome organization and normal progress through mitosis. .
Accessions	ENST00000561593.5 ENST00000566067.5 ENST00000626059.2 H3BMP6 ENST00000440851.6 [Q96BT3-1] ENST00000562462.5 H3BQ71 H3BQJ0 I3L4F8 ENST00000562338.1 Q96BT3 ENST00000562513.6 ENST00000564817.5 ENST00000566758.5 ENST00000562787.6 [Q96BT3-1] H3BUW2 H3BTS2 H3BTR4 ENST00000565114.5 ENST00000568069.5 H3BQS6 H3BN05 ENST00000565713.5

CENPT report