I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 19% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 19% ± 3% |
Insufficient scRNA-seq data for expression of CENPO at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 483.28 | 2640 / 2642 | 99% | 8.50 | 701 / 705 |
| uterus | 100% | 562.78 | 170 / 170 | 98% | 10.05 | 452 / 459 |
| skin | 100% | 747.51 | 1808 / 1809 | 98% | 8.47 | 464 / 472 |
| esophagus | 100% | 419.80 | 1441 / 1445 | 98% | 8.60 | 180 / 183 |
| breast | 100% | 735.10 | 459 / 459 | 98% | 6.79 | 1093 / 1118 |
| bladder | 100% | 386.76 | 21 / 21 | 97% | 7.27 | 490 / 504 |
| stomach | 99% | 305.94 | 356 / 359 | 98% | 7.21 | 280 / 286 |
| intestine | 100% | 412.67 | 962 / 966 | 97% | 7.25 | 510 / 527 |
| ovary | 100% | 656.85 | 180 / 180 | 96% | 6.55 | 412 / 430 |
| lung | 100% | 563.19 | 577 / 578 | 96% | 7.17 | 1108 / 1155 |
| prostate | 100% | 503.53 | 245 / 245 | 88% | 3.37 | 442 / 502 |
| thymus | 100% | 544.13 | 653 / 653 | 84% | 3.83 | 510 / 605 |
| adrenal gland | 100% | 523.99 | 258 / 258 | 73% | 2.99 | 168 / 230 |
| kidney | 99% | 371.73 | 88 / 89 | 70% | 2.40 | 635 / 901 |
| pancreas | 78% | 137.25 | 255 / 328 | 85% | 3.35 | 151 / 178 |
| liver | 81% | 177.09 | 184 / 226 | 51% | 2.37 | 209 / 406 |
| adipose | 100% | 792.94 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 632.48 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 10.78 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 2.57 | 1 / 1 |
| blood vessel | 100% | 319.99 | 1331 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 8.38 | 28 / 29 |
| heart | 96% | 239.77 | 829 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 93% | 4.16 | 74 / 80 |
| muscle | 89% | 170.27 | 713 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 82% | 517.41 | 762 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0034508 | Biological process | centromere complex assembly |
| GO_0007059 | Biological process | chromosome segregation |
| GO_0016604 | Cellular component | nuclear body |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0031511 | Cellular component | Mis6-Sim4 complex |
| GO_0000939 | Cellular component | inner kinetochore |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CENPO |
| Protein name | Centromere protein O (CENP-O) (Interphase centromere complex protein 36) |
| Synonyms | MCM21R ICEN36 |
| Description | FUNCTION: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Modulates the kinetochore-bound levels of NDC80 complex. . |
| Accessions | Q9BU64 ENST00000473706.5 [Q9BU64-2] ENST00000260662.2 [Q9BU64-1] ENST00000380834.7 [Q9BU64-1] |
