Mis6-Sim4 complex

I. Literature review

[source]
NameMis6-Sim4 complex
IDGO_0031511
collection_id

Cellular component

Exact synonym

Mis6-Mal2-Sim4 centromere complex, Sim4 complex

Description

A protein complex that forms part of the inner kinetochore, which is involved in the loading of the centromeric histone h3 variant CENP-A onto centromeres and in centromere specific heterochromatin formation. The complex contains about 12 proteins, of which two are known as Mis6 and Sim4 in S. pombe and CENP-I and CENP-H in human.

Related synonym

Mcm21

External URL
Genes