Name | Mis6-Sim4 complex |
ID | GO_0031511 |
collection_id | Cellular component |
Exact synonym | Mis6-Mal2-Sim4 centromere complex, Sim4 complex |
Description | A protein complex that forms part of the inner kinetochore, which is involved in the loading of the centromeric histone h3 variant CENP-A onto centromeres and in centromere specific heterochromatin formation. The complex contains about 12 proteins, of which two are known as Mis6 and Sim4 in S. pombe and CENP-I and CENP-H in human. |
Related synonym | Mcm21 |
External URL | |
Genes |