CEACAM8 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CEACAM8 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CEACAM8 at tissue level.

III. Associated gene sets

GO_0006955Biological processimmune response
GO_0007157Biological processheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO_0005615Cellular componentextracellular space
GO_0009986Cellular componentcell surface
GO_0098552Cellular componentside of membrane
GO_0035577Cellular componentazurophil granule membrane
GO_0070062Cellular componentextracellular exosome
GO_0070821Cellular componenttertiary granule membrane
GO_0035579Cellular componentspecific granule membrane
GO_0005886Cellular componentplasma membrane
GO_0046982Molecular functionprotein heterodimerization activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCEACAM8
Protein nameCEA cell adhesion molecule 8
Carcinoembryonic antigen-related cell adhesion molecule 8 (CD67 antigen) (Carcinoembryonic antigen CGM6) (Non-specific cross-reacting antigen NCA-95) (CD antigen CD66b)
Carcinoembryonic antigen-related cell adhesion molecule 8 (cDNA, FLJ93041, Homo sapiens carcinoembryonic antigen-related cell adhesionmolecule 8 (CEACAM8), mRNA)
SynonymshCG_21882
CGM6
DescriptionFUNCTION: Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner . Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 . Heterophilic interaction with CEACAM8 occurs in activated neutrophils . .

AccessionsM0R1X3
ENST00000244336.10
ENST00000599005.1
Q0Z7S6
P31997