CEACAM3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CEACAM3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CEACAM3 at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0002682Biological processregulation of immune system process
GO_0009986Cellular componentcell surface
GO_0035579Cellular componentspecific granule membrane
GO_0005886Cellular componentplasma membrane
GO_0005515Molecular functionprotein binding
GO_1990782Molecular functionprotein tyrosine kinase binding

IV. Literature review

[source]
Gene nameCEACAM3
Protein nameCarcinoembryonic antigen-related cell adhesion molecule 3 (Carcinoembryonic antigen CGM1) (CD antigen CD66d)
CEA cell adhesion molecule 3
Carcinoembryonic antigen-related cell adhesion molecule 3, isoform CRA_c (cDNA FLJ51937, highly similar to Carcinoembryonic antigen-related celladhesion molecule 6)
SynonymsCGM1
hCG_22311
CD66D
DescriptionFUNCTION: Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis. .

AccessionsM0QXR5
ENST00000357396.8 [P40198-1]
ENST00000630848.2 [P40198-3]
ENST00000596544.1
P40198
ENST00000344550.4 [P40198-3]
B7Z5B4
ENST00000415495.5 [P40198-2]