CDT1 | OmnibusX

Name	Number of supported studies	Average coverage
B cell	4 studies	24% ± 5%	Explore
hematopoietic precursor cell	3 studies	24% ± 4%	Explore
pro-B cell	3 studies	20% ± 1%	Explore
epithelial cell	3 studies	19% ± 3%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CDT1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
skin	100%	822.25	1806 / 1809	96%	35.99	452 / 472
lung	78%	212.56	451 / 578	86%	31.21	990 / 1155
intestine	61%	318.94	592 / 966	96%	59.65	504 / 527
stomach	55%	198.11	199 / 359	96%	53.00	275 / 286
esophagus	48%	361.05	699 / 1445	98%	47.65	180 / 183
bladder	52%	72.95	11 / 21	94%	49.25	473 / 504
brain	87%	151.08	2290 / 2642	57%	14.16	404 / 705
thymus	69%	88.19	451 / 653	75%	23.73	452 / 605
ovary	41%	48.45	74 / 180	99%	38.73	425 / 430
breast	54%	84.92	250 / 459	80%	22.39	892 / 1118
uterus	29%	42.88	49 / 170	99%	75.41	456 / 459
lymph node	0%	0	0 / 0	100%	90.65	29 / 29
tonsil	0%	0	0 / 0	100%	85.14	45 / 45
ureter	0%	0	0 / 0	100%	49.60	1 / 1
spleen	99%	486.00	239 / 241	0%	0	0 / 0
adrenal gland	71%	107.97	184 / 258	27%	10.18	62 / 230
prostate	69%	111.00	168 / 245	24%	3.70	122 / 502
pancreas	24%	28.77	78 / 328	66%	14.61	118 / 178
liver	31%	71.78	69 / 226	57%	14.01	231 / 406
kidney	53%	103.20	47 / 89	31%	4.52	280 / 901
peripheral blood	78%	1196.19	720 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	70%	12.95	56 / 80
adipose	40%	60.42	483 / 1204	0%	0	0 / 0
heart	21%	24.78	178 / 861	0%	0	0 / 0
blood vessel	20%	24.91	263 / 1335	0%	0	0 / 0
muscle	1%	0.71	7 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0000278	Biological process	mitotic cell cycle
GO_0045786	Biological process	negative regulation of cell cycle
GO_0051315	Biological process	attachment of mitotic spindle microtubules to kinetochore
GO_0051301	Biological process	cell division
GO_2000105	Biological process	positive regulation of DNA-templated DNA replication
GO_0045740	Biological process	positive regulation of DNA replication
GO_0030174	Biological process	regulation of DNA-templated DNA replication initiation
GO_0035563	Biological process	positive regulation of chromatin binding
GO_0072708	Biological process	response to sorbitol
GO_0033262	Biological process	regulation of nuclear cell cycle DNA replication
GO_2000104	Biological process	negative regulation of DNA-templated DNA replication
GO_0071163	Biological process	DNA replication preinitiation complex assembly
GO_0000076	Biological process	DNA replication checkpoint signaling
GO_0000776	Cellular component	kinetochore
GO_0005654	Cellular component	nucleoplasm
GO_0016604	Cellular component	nuclear body
GO_0005634	Cellular component	nucleus
GO_0003677	Molecular function	DNA binding
GO_0070182	Molecular function	DNA polymerase binding
GO_0003682	Molecular function	chromatin binding
GO_0005515	Molecular function	protein binding

Gene name	CDT1
Protein name	CDT1 protein Chromatin licensing and DNA replication factor 1 DNA replication factor Cdt1 (Double parked homolog) (DUP)
Synonyms
Description	FUNCTION: Required for both DNA replication and mitosis . DNA replication licensing factor, required for pre-replication complex assembly. Cooperates with CDC6 and the origin recognition complex (ORC) during G1 phase of the cell cycle to promote the loading of the mini-chromosome maintenance (MCM) complex onto DNA to generate pre-replication complexes (pre-RC). Required also for mitosis by promoting stable kinetochore-microtubule attachments . Potential oncogene (By similarity). .
Accessions	Q9H211 A0PJB2 ENST00000569140.1 ENST00000301019.9 H3BSY1

CDT1 report