CDIPT report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006661Biological processphosphatidylinositol biosynthetic process
GO_0005794Cellular componentGolgi apparatus
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0003881Molecular functionCDP-diacylglycerol-inositol 3-phosphatidyltransferase activity
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameCDIPT
Protein nameCDP-diacylglycerol--inositol 3-phosphatidyltransferase (EC 2.7.8.11) (Phosphatidylinositol synthase) (PI synthase) (PtdIns synthase)
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (cDNA FLJ16129 fis, clone BRACE2039823, highly similar to CDP-diacylglycerol--inositol3-phosphatidyltransferase)
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (EC 2.7.8.11)
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
SynonymsPIS1
hCG_21626
PIS
DescriptionFUNCTION: Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme. .

AccessionsENST00000561555.5
O14735
ENST00000564296.5
A8K3L7
ENST00000569956.5 [O14735-1]
ENST00000570016.5 [O14735-1]
B3KY94
H3BUR9
H3BTJ7
ENST00000566113.5 [O14735-3]
ENST00000219789.11 [O14735-1]
ENST00000563415.1
B3KSW0