CDHR2 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of CDHR2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	100%	1639.06	89 / 89	67%	26.05	604 / 901
intestine	75%	5802.22	729 / 966	86%	29.19	451 / 527
stomach	77%	497.65	275 / 359	83%	26.82	237 / 286
liver	100%	3865.33	226 / 226	52%	17.47	213 / 406
pancreas	38%	17.12	123 / 328	83%	34.65	147 / 178
brain	87%	95.24	2308 / 2642	10%	0.41	70 / 705
spleen	83%	37.26	199 / 241	0%	0	0 / 0
peripheral blood	69%	63.82	642 / 929	0%	0	0 / 0
esophagus	14%	12.96	207 / 1445	44%	18.77	81 / 183
lung	32%	13.84	183 / 578	15%	4.40	171 / 1155
skin	38%	14.13	685 / 1809	1%	0.07	7 / 472
adrenal gland	26%	7.55	68 / 258	10%	0.85	24 / 230
bladder	0%	0	0 / 21	23%	6.41	114 / 504
uterus	11%	8.41	18 / 170	7%	1.34	30 / 459
breast	14%	14.35	66 / 459	1%	0.04	8 / 1118
heart	13%	4.35	113 / 861	0%	0	0 / 0
prostate	10%	3.96	24 / 245	1%	0.03	4 / 502
thymus	10%	3.13	65 / 653	0%	0.02	3 / 605
ovary	6%	2.12	11 / 180	1%	0.10	3 / 430
adipose	5%	2.93	58 / 1204	0%	0	0 / 0
blood vessel	1%	0.78	17 / 1335	0%	0	0 / 0
muscle	1%	0.66	10 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0032532	Biological process	regulation of microvillus length
GO_0060243	Biological process	negative regulation of cell growth involved in contact inhibition
GO_0030855	Biological process	epithelial cell differentiation
GO_0044331	Biological process	cell-cell adhesion mediated by cadherin
GO_1904970	Biological process	brush border assembly
GO_0007156	Biological process	homophilic cell adhesion via plasma membrane adhesion molecules
GO_0090675	Biological process	intermicrovillar adhesion
GO_0098609	Biological process	cell-cell adhesion
GO_0031526	Cellular component	brush border membrane
GO_0005903	Cellular component	brush border
GO_0005902	Cellular component	microvillus
GO_0016324	Cellular component	apical plasma membrane
GO_0005886	Cellular component	plasma membrane
GO_0031528	Cellular component	microvillus membrane
GO_0070062	Cellular component	extracellular exosome
GO_0070161	Cellular component	anchoring junction
GO_0050839	Molecular function	cell adhesion molecule binding
GO_0005509	Molecular function	calcium ion binding
GO_0005515	Molecular function	protein binding

Gene name	CDHR2
Protein name	Cadherin-related family member 2 (Protocadherin LKC) (PC-LKC) (Protocadherin-24) Cadherin related family member 2
Synonyms	PCLKC PCDH24
Description	FUNCTION: Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR5 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation . May also play a role in cell-cell adhesion and contact inhibition in epithelial cells . .
Accessions	D6REJ3 ENST00000510124.5 ENST00000510636.5 ENST00000261944.10 Q9BYE9

CDHR2 report