CDCA7L report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CDCA7L at tissue level.

III. Associated gene sets

GO_0008284Biological processpositive regulation of cell population proliferation
GO_0006355Biological processregulation of DNA-templated transcription
GO_0005730Cellular componentnucleolus
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0001650Cellular componentfibrillar center
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCDCA7L
Protein nameCell division cycle associated 7 like
Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2)
SynonymsJPO2
R1
HR1
DescriptionFUNCTION: Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1. .

AccessionsENST00000447180.5
Q96GN5
ENST00000406877.8 [Q96GN5-1]
ENST00000435031.1
C9JFL7
H7C1J6
ENST00000356195.9 [Q96GN5-4]
ENST00000457951.5
ENST00000373934.4 [Q96GN5-5]
ENST00000435717.1
C9IZR6
C9J8L0