Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| B cell | 15 studies | 24% ± 7% | |
| naive B cell | 15 studies | 25% ± 5% | |
| plasmacytoid dendritic cell | 10 studies | 23% ± 6% | |
| pro-B cell | 5 studies | 36% ± 7% | |
| memory B cell | 5 studies | 18% ± 4% | |
| hematopoietic precursor cell | 4 studies | 24% ± 9% | |
| precursor B cell | 4 studies | 31% ± 9% | |
| immature B cell | 4 studies | 31% ± 12% | |
| mesothelial cell | 3 studies | 28% ± 16% | |
| epithelial cell | 3 studies | 23% ± 8% | |
| germinal center B cell | 3 studies | 21% ± 3% | |
| granulocyte monocyte progenitor cell | 3 studies | 20% ± 3% |
Insufficient scRNA-seq data for expression of CDCA7L at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 100% | 1058.30 | 180 / 180 | 97% | 27.26 | 417 / 430 |
| intestine | 100% | 905.70 | 964 / 966 | 97% | 23.62 | 510 / 527 |
| lung | 99% | 663.90 | 575 / 578 | 96% | 25.97 | 1111 / 1155 |
| esophagus | 99% | 666.41 | 1424 / 1445 | 96% | 22.90 | 175 / 183 |
| thymus | 100% | 1054.89 | 653 / 653 | 93% | 21.77 | 560 / 605 |
| stomach | 100% | 1045.98 | 359 / 359 | 91% | 18.77 | 260 / 286 |
| uterus | 99% | 679.58 | 169 / 170 | 88% | 21.77 | 405 / 459 |
| pancreas | 100% | 722.78 | 327 / 328 | 87% | 9.99 | 155 / 178 |
| breast | 91% | 569.10 | 417 / 459 | 84% | 15.20 | 937 / 1118 |
| prostate | 95% | 492.96 | 232 / 245 | 76% | 9.07 | 384 / 502 |
| skin | 100% | 1700.23 | 1807 / 1809 | 70% | 17.97 | 331 / 472 |
| bladder | 100% | 318.00 | 21 / 21 | 61% | 12.73 | 305 / 504 |
| brain | 72% | 182.14 | 1903 / 2642 | 85% | 18.39 | 598 / 705 |
| kidney | 42% | 114.18 | 37 / 89 | 73% | 11.99 | 661 / 901 |
| liver | 65% | 154.77 | 148 / 226 | 36% | 3.87 | 146 / 406 |
| spleen | 99% | 613.88 | 239 / 241 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 38.95 | 28 / 29 |
| eye | 0% | 0 | 0 / 0 | 96% | 17.70 | 77 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 21.94 | 43 / 45 |
| adipose | 92% | 435.47 | 1112 / 1204 | 0% | 0 | 0 / 0 |
| heart | 89% | 736.64 | 770 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 83% | 751.13 | 775 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 55% | 166.48 | 737 / 1335 | 0% | 0 | 0 / 0 |
| adrenal gland | 13% | 22.11 | 33 / 258 | 28% | 2.68 | 65 / 230 |
| muscle | 24% | 53.88 | 192 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0006355 | Biological process | regulation of DNA-templated transcription |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0001650 | Cellular component | fibrillar center |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CDCA7L |
| Protein name | Cell division cycle associated 7 like Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2) |
| Synonyms | JPO2 R1 HR1 |
| Description | FUNCTION: Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1. . |
| Accessions | ENST00000447180.5 Q96GN5 ENST00000406877.8 [Q96GN5-1] ENST00000435031.1 C9JFL7 H7C1J6 ENST00000356195.9 [Q96GN5-4] ENST00000457951.5 ENST00000373934.4 [Q96GN5-5] ENST00000435717.1 C9IZR6 C9J8L0 |