CDCA5 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CDCA5 at tissue level.

III. Associated gene sets

GO_0007076Biological processmitotic chromosome condensation
GO_0051301Biological processcell division
GO_0000278Biological processmitotic cell cycle
GO_0007080Biological processmitotic metaphase chromosome alignment
GO_0031536Biological processpositive regulation of exit from mitosis
GO_0007064Biological processmitotic sister chromatid cohesion
GO_0006302Biological processdouble-strand break repair
GO_0000775Cellular componentchromosome, centromeric region
GO_0005694Cellular componentchromosome
GO_0005829Cellular componentcytosol
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0044877Molecular functionprotein-containing complex binding
GO_0005515Molecular functionprotein binding
GO_0003682Molecular functionchromatin binding

IV. Literature review

[source]
Gene nameCDCA5
Protein nameCell division cycle associated 5
Sororin (Cell division cycle-associated protein 5) (p35)
Synonyms
DescriptionFUNCTION: Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPL which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair. .

AccessionsH0YCZ9
Q96FF9
B5MBX0
ENST00000527430.1
ENST00000524733.5
H0YCT9
H0YCL8
ENST00000275517.8
H0YCR8
ENST00000404147.3
ENST00000525464.1
ENST00000529290.5