Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 17 studies | 36% ± 19% | |
| oligodendrocyte | 15 studies | 52% ± 19% | |
| oligodendrocyte precursor cell | 13 studies | 44% ± 22% | |
| microglial cell | 10 studies | 27% ± 7% | |
| endothelial cell | 9 studies | 30% ± 9% | |
| glutamatergic neuron | 8 studies | 42% ± 24% | |
| adipocyte | 8 studies | 31% ± 7% | |
| GABAergic neuron | 7 studies | 46% ± 22% | |
| smooth muscle cell | 7 studies | 26% ± 7% | |
| interneuron | 6 studies | 40% ± 22% | |
| epithelial cell | 5 studies | 28% ± 7% | |
| ciliated cell | 5 studies | 27% ± 6% | |
| fibroblast | 5 studies | 24% ± 9% | |
| cardiac muscle cell | 4 studies | 29% ± 5% | |
| endothelial cell of lymphatic vessel | 4 studies | 21% ± 3% | |
| pericyte | 4 studies | 26% ± 11% | |
| GABAergic interneuron | 3 studies | 24% ± 1% | |
| Mueller cell | 3 studies | 26% ± 5% | |
| amacrine cell | 3 studies | 25% ± 8% | |
| glycinergic amacrine cell | 3 studies | 19% ± 3% | |
| hepatocyte | 3 studies | 60% ± 19% | |
| abnormal cell | 3 studies | 30% ± 18% | |
| ependymal cell | 3 studies | 37% ± 14% | |
| basal cell | 3 studies | 26% ± 7% | |
| neuron | 3 studies | 57% ± 22% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 100% | 1496.33 | 327 / 328 | 98% | 8.18 | 175 / 178 |
| lung | 99% | 1470.40 | 575 / 578 | 98% | 7.51 | 1135 / 1155 |
| thymus | 100% | 3275.89 | 653 / 653 | 98% | 9.75 | 590 / 605 |
| kidney | 100% | 2188.51 | 89 / 89 | 97% | 10.53 | 878 / 901 |
| brain | 98% | 2212.15 | 2582 / 2642 | 100% | 18.25 | 703 / 705 |
| intestine | 100% | 1928.45 | 966 / 966 | 97% | 8.28 | 512 / 527 |
| stomach | 100% | 2248.62 | 359 / 359 | 97% | 8.81 | 277 / 286 |
| prostate | 100% | 2639.20 | 245 / 245 | 96% | 8.94 | 483 / 502 |
| bladder | 100% | 2949.29 | 21 / 21 | 95% | 6.67 | 477 / 504 |
| esophagus | 98% | 1585.10 | 1417 / 1445 | 96% | 9.41 | 176 / 183 |
| ovary | 99% | 1622.47 | 179 / 180 | 93% | 5.38 | 402 / 430 |
| liver | 100% | 2586.07 | 226 / 226 | 93% | 8.52 | 376 / 406 |
| skin | 99% | 2242.04 | 1797 / 1809 | 91% | 6.65 | 429 / 472 |
| adrenal gland | 98% | 1707.12 | 253 / 258 | 91% | 12.52 | 210 / 230 |
| uterus | 100% | 1550.86 | 170 / 170 | 81% | 5.32 | 374 / 459 |
| breast | 100% | 2627.83 | 459 / 459 | 78% | 4.11 | 876 / 1118 |
| adipose | 100% | 2883.60 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 3166.32 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| heart | 96% | 1517.05 | 829 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 91% | 6.78 | 73 / 80 |
| spleen | 87% | 603.71 | 210 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 84% | 6.42 | 38 / 45 |
| muscle | 51% | 437.24 | 407 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 17% | 0.48 | 5 / 29 |
| peripheral blood | 5% | 27.83 | 50 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0060271 | Biological process | cilium assembly |
| GO_0006281 | Biological process | DNA repair |
| GO_0006470 | Biological process | protein dephosphorylation |
| GO_0007096 | Biological process | regulation of exit from mitosis |
| GO_0007095 | Biological process | mitotic G2 DNA damage checkpoint signaling |
| GO_1904668 | Biological process | positive regulation of ubiquitin protein ligase activity |
| GO_0000226 | Biological process | microtubule cytoskeleton organization |
| GO_0032467 | Biological process | positive regulation of cytokinesis |
| GO_0005730 | Cellular component | nucleolus |
| GO_0072686 | Cellular component | mitotic spindle |
| GO_0000922 | Cellular component | spindle pole |
| GO_0005813 | Cellular component | centrosome |
| GO_0005634 | Cellular component | nucleus |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0017018 | Molecular function | myosin phosphatase activity |
| GO_0004722 | Molecular function | protein serine/threonine phosphatase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0004725 | Molecular function | protein tyrosine phosphatase activity |
| Gene name | CDC14B |
| Protein name | Alternative protein CDC14B Cell division cycle 14B Dual specificity protein phosphatase CDC14B (EC 3.1.3.16) (EC 3.1.3.48) (CDC14 cell division cycle 14 homolog B) |
| Synonyms | |
| Description | FUNCTION: Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome (APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases. . |
| Accessions | H7C3U8 ENST00000415608.1 H0Y577 Q5JU07 ENST00000474602.5 [O60729-3] ENST00000375242.7 [O60729-5] O60729 ENST00000463569.5 [O60729-4] A0A9L9PY50 ENST00000412285.6 ENST00000375241.6 [O60729-1] L8E9I0 ENST00000452280.5 ENST00000375240.7 [O60729-2] ENST00000481149.2 |