CCL3L1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CCL3L1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CCL3L1 at tissue level.

III. Associated gene sets

GO_0061844Biological processantimicrobial humoral immune response mediated by antimicrobial peptide
GO_0008285Biological processnegative regulation of cell population proliferation
GO_0070098Biological processchemokine-mediated signaling pathway
GO_0030335Biological processpositive regulation of cell migration
GO_0006954Biological processinflammatory response
GO_0043547Biological processpositive regulation of GTPase activity
GO_0048245Biological processeosinophil chemotaxis
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0048020Molecular functionCCR chemokine receptor binding
GO_0005515Molecular functionprotein binding
GO_0008009Molecular functionchemokine activity

IV. Literature review

[source]
Gene nameCCL3L1
Protein nameC-C motif chemokine 3-like 1 (G0/G1 switch regulatory protein 19-2) (LD78-beta(1-70)) (PAT 464.2) (Small-inducible cytokine A3-like 1) (Tonsillar lymphocyte LD78 beta protein) [Cleaved into: LD78-beta(3-70); LD78-beta(5-70)]
SynonymsSCYA3L1;
G0S19-2
D17S1718
CCL3L3
DescriptionFUNCTION: Chemotactic for lymphocytes and monocytes. Is a ligand for CCR1, CCR3 and CCR5. Is an inhibitor of HIV-1-infection. The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection. LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5. .

AccessionsENST00000621940.2
ENST00000619989.1
ENST00000615140.2
ENST00000612067.2
P16619