CBLIF report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CBLIF at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CBLIF at tissue level.

III. Associated gene sets

GO_0015889Biological processcobalamin transport
GO_0006824Biological processcobalt ion transport
GO_0005902Cellular componentmicrovillus
GO_0016324Cellular componentapical plasma membrane
GO_0005615Cellular componentextracellular space
GO_0043202Cellular componentlysosomal lumen
GO_0005768Cellular componentendosome
GO_0005576Cellular componentextracellular region
GO_0031419Molecular functioncobalamin binding
GO_0140355Molecular functioncargo receptor ligand activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCBLIF
Protein nameCobalamin binding intrinsic factor
Cobalamin binding intrinsic factor (Gastric intrinsic factor) (Intrinsic factor) (IF) (INF)
SynonymsGIF
IFMH
DescriptionFUNCTION: Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the CBLIF-cobalamin complex is internalized via receptor-mediated endocytosis.

AccessionsP27352
ENST00000525058.5
ENST00000257248.3 [P27352-1]
E9PM21