CARD17P report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CARD17P at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CARD17P at tissue level.

III. Associated gene sets

GO_0071222Biological processcellular response to lipopolysaccharide
GO_0042981Biological processregulation of apoptotic process
GO_0032691Biological processnegative regulation of interleukin-1 beta production
GO_0032991Cellular componentprotein-containing complex
GO_0005737Cellular componentcytoplasm
GO_0004869Molecular functioncysteine-type endopeptidase inhibitor activity
GO_0089720Molecular functioncaspase binding
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCARD17P
Protein namePutative caspase recruitment domain-containing protein 17P (Caspase-1 inhibitor INCA) (Inhibitory caspase recruitment domain protein)
SynonymsCARD17
INCA
DescriptionFUNCTION: Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation. .

AccessionsQ5XLA6