CAPN10 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CAPN10 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CAPN10 at tissue level.

III. Associated gene sets

GO_0032024Biological processpositive regulation of insulin secretion
GO_0006921Biological processcellular component disassembly involved in execution phase of apoptosis
GO_0046326Biological processpositive regulation of glucose import
GO_0097050Biological processtype B pancreatic cell apoptotic process
GO_2000676Biological processpositive regulation of type B pancreatic cell apoptotic process
GO_0032869Biological processcellular response to insulin stimulus
GO_0006508Biological processproteolysis
GO_0032956Biological processregulation of actin cytoskeleton organization
GO_0032388Biological processpositive regulation of intracellular transport
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0005739Cellular componentmitochondrion
GO_0004198Molecular functioncalcium-dependent cysteine-type endopeptidase activity
GO_0000149Molecular functionSNARE binding
GO_0008092Molecular functioncytoskeletal protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCAPN10
Protein nameCalpain-10 (EC 3.4.22.-) (Calcium-activated neutral proteinase 10) (CANP 10)
Calpain 10
SynonymsKIAA1845
DescriptionFUNCTION: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. May play a role in insulin-stimulated glucose uptake. .

AccessionsENST00000352879.8 [Q9HC96-8]
ENST00000391984.7 [Q9HC96-1]
ENST00000357048.8 [Q9HC96-4]
ENST00000270361.15 [Q9HC96-6]
ENST00000426297.1
ENST00000270364.11 [Q9HC96-7]
H7C2P1
Q9HC96
ENST00000416591.5 [Q9HC96-5]
ENST00000432084.2
H7C251
B7WPF5
ENST00000404753.7
ENST00000354082.8 [Q9HC96-3]
ENST00000391983.7 [Q9HC96-2]