CALCB report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CALCB at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CALCB at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0051480Biological processregulation of cytosolic calcium ion concentration
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0006874Biological processintracellular calcium ion homeostasis
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0031716Molecular functioncalcitonin receptor binding
GO_0005515Molecular functionprotein binding
GO_0005184Molecular functionneuropeptide hormone activity

IV. Literature review

[source]
Gene nameCALCB
Protein nameCalcitonin gene-related peptide 2 (Beta-type CGRP) (Beta-CGRP) (Calcitonin gene-related peptide II) (CGRP-II)
Calcitonin related polypeptide beta
SynonymsCALC2
DescriptionFUNCTION: CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role.

AccessionsENST00000324229.11
ENST00000523376.5
P10092
E7ESF5
ENST00000533448.1