Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 19 studies | 63% ± 20% | |
glutamatergic neuron | 13 studies | 66% ± 25% | |
smooth muscle cell | 12 studies | 52% ± 16% | |
GABAergic neuron | 11 studies | 57% ± 23% | |
oligodendrocyte precursor cell | 11 studies | 34% ± 17% | |
pericyte | 11 studies | 36% ± 17% | |
mesothelial cell | 9 studies | 45% ± 12% | |
fibroblast | 9 studies | 39% ± 14% | |
endothelial cell | 6 studies | 50% ± 10% | |
retinal cone cell | 6 studies | 72% ± 31% | |
cardiac muscle cell | 6 studies | 82% ± 13% | |
neuron | 5 studies | 41% ± 12% | |
microglial cell | 5 studies | 41% ± 18% | |
retinal rod cell | 5 studies | 78% ± 27% | |
interneuron | 5 studies | 56% ± 24% | |
myofibroblast cell | 4 studies | 47% ± 33% | |
ON-bipolar cell | 4 studies | 56% ± 28% | |
retinal ganglion cell | 4 studies | 41% ± 17% | |
oligodendrocyte | 4 studies | 34% ± 18% | |
GABAergic interneuron | 3 studies | 65% ± 8% | |
Purkinje cell | 3 studies | 53% ± 32% | |
epithelial cell | 3 studies | 46% ± 26% | |
macrophage | 3 studies | 26% ± 9% | |
retinal bipolar neuron | 3 studies | 59% ± 27% | |
GABAergic amacrine cell | 3 studies | 41% ± 18% | |
Mueller cell | 3 studies | 59% ± 16% | |
OFF-bipolar cell | 3 studies | 58% ± 15% | |
amacrine cell | 3 studies | 44% ± 14% | |
glycinergic amacrine cell | 3 studies | 43% ± 12% | |
rod bipolar cell | 3 studies | 66% ± 33% | |
retinal pigment epithelial cell | 3 studies | 77% ± 18% | |
ependymal cell | 3 studies | 40% ± 8% | |
granule cell | 3 studies | 73% ± 14% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 99% | 1432.98 | 242 / 245 | 97% | 2.84 | 486 / 502 |
brain | 91% | 1879.50 | 2403 / 2642 | 93% | 4.40 | 653 / 705 |
adrenal gland | 94% | 1191.38 | 242 / 258 | 87% | 5.95 | 199 / 230 |
intestine | 100% | 2161.85 | 963 / 966 | 40% | 0.93 | 213 / 527 |
pancreas | 94% | 638.33 | 307 / 328 | 44% | 1.35 | 79 / 178 |
kidney | 58% | 292.27 | 52 / 89 | 72% | 2.19 | 645 / 901 |
esophagus | 87% | 3451.45 | 1262 / 1445 | 41% | 1.16 | 75 / 183 |
bladder | 90% | 2657.76 | 19 / 21 | 27% | 0.67 | 135 / 504 |
uterus | 98% | 1633.63 | 167 / 170 | 14% | 0.44 | 66 / 459 |
ovary | 100% | 2027.56 | 180 / 180 | 9% | 0.15 | 38 / 430 |
lung | 90% | 575.81 | 519 / 578 | 18% | 0.60 | 208 / 1155 |
blood vessel | 98% | 1182.89 | 1312 / 1335 | 0% | 0 | 0 / 0 |
breast | 72% | 574.27 | 330 / 459 | 23% | 1.20 | 262 / 1118 |
stomach | 53% | 1037.70 | 190 / 359 | 41% | 1.01 | 117 / 286 |
heart | 92% | 1778.16 | 796 / 861 | 0% | 0 | 0 / 0 |
liver | 63% | 361.19 | 143 / 226 | 20% | 0.41 | 81 / 406 |
thymus | 48% | 232.32 | 313 / 653 | 32% | 0.73 | 191 / 605 |
skin | 70% | 430.84 | 1269 / 1809 | 3% | 0.08 | 15 / 472 |
adipose | 48% | 316.10 | 573 / 1204 | 0% | 0 | 0 / 0 |
peripheral blood | 8% | 54.62 | 78 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 7% | 0.55 | 2 / 29 |
spleen | 3% | 11.67 | 7 / 241 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 3% | 0.11 | 2 / 80 |
tonsil | 0% | 0 | 0 / 0 | 2% | 0.10 | 1 / 45 |
muscle | 2% | 6.50 | 13 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007601 | Biological process | visual perception |
GO_0072659 | Biological process | protein localization to plasma membrane |
GO_0045933 | Biological process | positive regulation of muscle contraction |
GO_0098912 | Biological process | membrane depolarization during atrial cardiac muscle cell action potential |
GO_1901385 | Biological process | regulation of voltage-gated calcium channel activity |
GO_0007528 | Biological process | neuromuscular junction development |
GO_0070509 | Biological process | calcium ion import |
GO_0007268 | Biological process | chemical synaptic transmission |
GO_0086045 | Biological process | membrane depolarization during AV node cell action potential |
GO_0086091 | Biological process | regulation of heart rate by cardiac conduction |
GO_0099509 | Biological process | regulation of presynaptic cytosolic calcium ion concentration |
GO_1901843 | Biological process | positive regulation of high voltage-gated calcium channel activity |
GO_1904879 | Biological process | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel |
GO_0051928 | Biological process | positive regulation of calcium ion transport |
GO_0070588 | Biological process | calcium ion transmembrane transport |
GO_0098793 | Cellular component | presynapse |
GO_0005886 | Cellular component | plasma membrane |
GO_1990454 | Cellular component | L-type voltage-gated calcium channel complex |
GO_0005891 | Cellular component | voltage-gated calcium channel complex |
GO_0098684 | Cellular component | photoreceptor ribbon synapse |
GO_0086056 | Molecular function | voltage-gated calcium channel activity involved in AV node cell action potential |
GO_0051015 | Molecular function | actin filament binding |
GO_0086007 | Molecular function | voltage-gated calcium channel activity involved in cardiac muscle cell action potential |
GO_0005245 | Molecular function | voltage-gated calcium channel activity |
GO_0008331 | Molecular function | high voltage-gated calcium channel activity |
GO_0005515 | Molecular function | protein binding |
GO_0005262 | Molecular function | calcium channel activity |
GO_0099626 | Molecular function | voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels |
Gene name | CACNB2 |
Protein name | Calcium voltage-gated channel auxiliary subunit beta 2 Voltage-gated calcium channel beta 2 subunit splice variant CavB2dN4 Voltage-dependent L-type calcium channel subunit beta-2 (Calcium channel voltage-dependent subunit beta 2) Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB) |
Synonyms | CACNLB2 MYSB |
Description | FUNCTION: Beta subunit of voltage-dependent calcium channels which contributes to the function of the calcium channel by increasing peak calcium current (By similarity). Plays a role in shifting voltage dependencies of activation and inactivation of the channel (By similarity). May modulate G protein inhibition (By similarity). May contribute to beta-adrenergic augmentation of Ca(2+) influx in cardiomyocytes, thereby regulating increases in heart rate and contractile force . Involved in membrane targeting of the alpha-1 subunit CACNA1C . . |
Accessions | ENST00000651928.1 ENST00000352115.10 [Q08289-8] ENST00000645287.2 [Q08289-9] ENST00000377329.10 [Q08289-3] ENST00000377331.8 ENST00000377328.5 ENST00000617363.4 ENST00000615785.4 ENST00000643096.2 ENST00000377319.9 [Q08289-6] ENST00000650685.1 ENST00000651330.1 A0A494C0C3 ENST00000647168.2 A0A494C1Q6 ENST00000324631.13 [Q08289-1] Q6TME0 ENST00000377315.6 [Q08289-5] A0A087WVX5 ENST00000652391.1 ENST00000396576.6 [Q08289-2] A0A494C0B2 A0A2R8YFX9 A0A494C044 A0A2U3TZM7 Q08289 ENST00000651468.1 A6PVM6 A0A2R8Y555 A0A494C0Z9 ENST00000652478.1 A0A494C184 A0A2R8Y7A6 A0A087WWJ0 ENST00000282343.13 [Q08289-4] ENST00000644004.1 |