Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 16 studies | 39% ± 19% | |
oligodendrocyte | 16 studies | 62% ± 18% | |
oligodendrocyte precursor cell | 14 studies | 55% ± 21% | |
glutamatergic neuron | 13 studies | 74% ± 22% | |
pericyte | 12 studies | 39% ± 17% | |
fibroblast | 12 studies | 39% ± 16% | |
GABAergic neuron | 11 studies | 40% ± 17% | |
smooth muscle cell | 11 studies | 38% ± 13% | |
endothelial cell | 10 studies | 43% ± 17% | |
adipocyte | 10 studies | 55% ± 19% | |
mast cell | 8 studies | 24% ± 10% | |
neuron | 6 studies | 61% ± 19% | |
interneuron | 6 studies | 33% ± 22% | |
microglial cell | 6 studies | 43% ± 20% | |
cardiac muscle cell | 6 studies | 61% ± 24% | |
retinal ganglion cell | 5 studies | 57% ± 28% | |
granule cell | 4 studies | 69% ± 14% | |
mesothelial cell | 4 studies | 36% ± 17% | |
OFF-bipolar cell | 4 studies | 51% ± 27% | |
ON-bipolar cell | 4 studies | 48% ± 26% | |
retina horizontal cell | 4 studies | 52% ± 16% | |
retinal cone cell | 4 studies | 57% ± 25% | |
GABAergic interneuron | 3 studies | 34% ± 2% | |
progenitor cell | 3 studies | 54% ± 24% | |
endocardial cell | 3 studies | 43% ± 10% | |
retinal bipolar neuron | 3 studies | 48% ± 27% | |
retinal rod cell | 3 studies | 43% ± 33% | |
amacrine cell | 3 studies | 39% ± 17% | |
connective tissue cell | 3 studies | 20% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
adrenal gland | 100% | 2709.16 | 258 / 258 | 96% | 36.97 | 221 / 230 |
thymus | 100% | 2722.26 | 652 / 653 | 95% | 11.77 | 573 / 605 |
prostate | 99% | 1739.73 | 242 / 245 | 93% | 12.54 | 467 / 502 |
brain | 97% | 2985.19 | 2575 / 2642 | 91% | 14.47 | 645 / 705 |
breast | 98% | 1457.98 | 450 / 459 | 76% | 5.09 | 848 / 1118 |
lung | 96% | 1056.52 | 554 / 578 | 73% | 8.31 | 840 / 1155 |
kidney | 80% | 720.07 | 71 / 89 | 81% | 9.54 | 728 / 901 |
uterus | 99% | 1860.15 | 168 / 170 | 54% | 5.98 | 250 / 459 |
esophagus | 74% | 1648.66 | 1074 / 1445 | 75% | 10.12 | 137 / 183 |
ovary | 100% | 1686.20 | 180 / 180 | 45% | 2.48 | 194 / 430 |
skin | 90% | 1558.45 | 1621 / 1809 | 50% | 4.10 | 238 / 472 |
stomach | 82% | 1142.83 | 295 / 359 | 52% | 3.90 | 148 / 286 |
bladder | 95% | 2553.81 | 20 / 21 | 38% | 2.78 | 189 / 504 |
intestine | 83% | 2859.78 | 798 / 966 | 33% | 2.00 | 174 / 527 |
muscle | 100% | 10544.28 | 803 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2795.49 | 1334 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 2335.14 | 1202 / 1204 | 0% | 0 | 0 / 0 |
heart | 95% | 2675.90 | 822 / 861 | 0% | 0 | 0 / 0 |
pancreas | 2% | 13.20 | 7 / 328 | 83% | 6.15 | 147 / 178 |
spleen | 83% | 727.10 | 200 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 82% | 8.84 | 37 / 45 |
eye | 0% | 0 | 0 / 0 | 20% | 0.71 | 16 / 80 |
liver | 2% | 10.26 | 4 / 226 | 8% | 0.38 | 33 / 406 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.07 | 1 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0060307 | Biological process | regulation of ventricular cardiac muscle cell membrane repolarization |
GO_1902514 | Biological process | regulation of calcium ion transmembrane transport via high voltage-gated calcium channel |
GO_0086002 | Biological process | cardiac muscle cell action potential involved in contraction |
GO_0051924 | Biological process | regulation of calcium ion transport |
GO_0098703 | Biological process | calcium ion import across plasma membrane |
GO_0061577 | Biological process | calcium ion transmembrane transport via high voltage-gated calcium channel |
GO_0086091 | Biological process | regulation of heart rate by cardiac conduction |
GO_1901843 | Biological process | positive regulation of high voltage-gated calcium channel activity |
GO_0086048 | Biological process | membrane depolarization during bundle of His cell action potential |
GO_0060402 | Biological process | calcium ion transport into cytosol |
GO_0098903 | Biological process | regulation of membrane repolarization during action potential |
GO_1904646 | Biological process | cellular response to amyloid-beta |
GO_0006816 | Biological process | calcium ion transport |
GO_0098992 | Cellular component | neuronal dense core vesicle |
GO_0005886 | Cellular component | plasma membrane |
GO_1990454 | Cellular component | L-type voltage-gated calcium channel complex |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005891 | Cellular component | voltage-gated calcium channel complex |
GO_0016529 | Cellular component | sarcoplasmic reticulum |
GO_0086057 | Molecular function | voltage-gated calcium channel activity involved in bundle of His cell action potential |
GO_0086007 | Molecular function | voltage-gated calcium channel activity involved in cardiac muscle cell action potential |
GO_0005245 | Molecular function | voltage-gated calcium channel activity |
GO_0046872 | Molecular function | metal ion binding |
Gene name | CACNA2D1 |
Protein name | Calcium voltage-gated channel auxiliary subunit alpha2delta 1 Uncharacterized protein CACNA2D1 Voltage-dependent calcium channel subunit alpha-2/delta-1 (Voltage-gated calcium channel subunit alpha-2/delta-1) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-1; Voltage-dependent calcium channel subunit delta-1] Dihydropyridine receptor alpha 2 subunit |
Synonyms | CACNL2A CCHL2A MHS3 |
Description | FUNCTION: The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel . Plays an important role in excitation-contraction coupling (By similarity). . |
Accessions | A0A994J595 ENST00000705962.1 ENST00000443883.2 Q9UDU5 Q9UIU0 H0Y715 O95026 ENST00000356860.8 [P54289-2] P54289 ENST00000705961.1 E7ERK3 ENST00000423588.1 ENST00000443883.2 [P54289-1] A0A994J5M8 Q9UDL7 |