CACNA1I | OmnibusX

Name	Number of supported studies	Average coverage
GABAergic neuron	3 studies	27% ± 6%	Explore
glutamatergic neuron	3 studies	42% ± 8%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CACNA1I at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	99%	2890.81	645 / 653	87%	7.56	529 / 605
brain	92%	2824.12	2425 / 2642	55%	2.67	391 / 705
adrenal gland	97%	1597.28	250 / 258	29%	1.46	66 / 230
ureter	0%	0	0 / 0	100%	1.32	1 / 1
spleen	85%	766.28	206 / 241	0%	0	0 / 0
lung	38%	201.58	222 / 578	20%	0.49	226 / 1155
peripheral blood	53%	391.50	497 / 929	0%	0	0 / 0
bladder	29%	183.24	6 / 21	22%	0.81	112 / 504
stomach	35%	156.90	125 / 359	5%	0.19	15 / 286
intestine	32%	433.35	309 / 966	5%	0.10	24 / 527
breast	9%	38.10	40 / 459	23%	0.63	253 / 1118
lymph node	0%	0	0 / 0	21%	0.35	6 / 29
esophagus	5%	20.93	70 / 1445	14%	0.46	26 / 183
pancreas	0%	0.85	1 / 328	13%	0.33	23 / 178
uterus	2%	7.74	4 / 170	9%	0.25	40 / 459
skin	3%	9.66	49 / 1809	6%	0.16	28 / 472
kidney	6%	52.75	5 / 89	2%	0.05	16 / 901
adipose	7%	29.35	87 / 1204	0%	0	0 / 0
liver	0%	0	0 / 226	7%	0.31	29 / 406
prostate	6%	23.16	14 / 245	0%	0.19	2 / 502
ovary	2%	5.10	3 / 180	4%	0.09	19 / 430
eye	0%	0	0 / 0	3%	0.14	2 / 80
blood vessel	2%	10.77	21 / 1335	0%	0	0 / 0
heart	1%	2.27	5 / 861	0%	0	0 / 0
muscle	0%	0.60	1 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45

GO_0007165	Biological process	signal transduction
GO_0098703	Biological process	calcium ion import across plasma membrane
GO_0019228	Biological process	neuronal action potential
GO_0030431	Biological process	sleep
GO_0005891	Cellular component	voltage-gated calcium channel complex
GO_0005886	Cellular component	plasma membrane
GO_0008331	Molecular function	high voltage-gated calcium channel activity
GO_0005245	Molecular function	voltage-gated calcium channel activity
GO_0005515	Molecular function	protein binding

Gene name	CACNA1I
Protein name	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage-gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3)
Synonyms	KIAA1120
Description	FUNCTION: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the 'low-voltage activated (LVA)' group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes. Gates in voltage ranges similar to, but higher than alpha 1G or alpha 1H (By similarity). .
Accessions	ENST00000402142.4 [Q9P0X4-1] ENST00000404898.5 [Q9P0X4-4] Q9P0X4 ENST00000401624.5 [Q9P0X4-2] ENST00000407673.5 [Q9P0X4-3]

CACNA1I report