CACNA1F | OmnibusX

Name	Number of supported studies	Average coverage
eye	4 studies	22% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	93%	219.41	429 / 459	36%	0.89	406 / 1118
lung	99%	180.81	573 / 578	20%	0.47	226 / 1155
kidney	96%	73.12	85 / 89	21%	0.44	187 / 901
thymus	96%	103.68	630 / 653	15%	0.27	88 / 605
pancreas	86%	50.72	281 / 328	16%	0.27	29 / 178
spleen	100%	212.85	241 / 241	0%	0	0 / 0
stomach	89%	74.85	321 / 359	6%	0.09	18 / 286
brain	93%	132.27	2446 / 2642	2%	0.03	15 / 705
adipose	93%	71.57	1118 / 1204	0%	0	0 / 0
intestine	86%	181.86	828 / 966	6%	0.14	34 / 527
esophagus	80%	41.64	1153 / 1445	11%	0.21	20 / 183
uterus	78%	39.51	132 / 170	13%	0.37	58 / 459
peripheral blood	90%	90.81	834 / 929	0%	0	0 / 0
prostate	74%	43.68	182 / 245	0%	0	0 / 502
skin	70%	49.67	1266 / 1809	4%	0.05	17 / 472
bladder	62%	29.86	13 / 21	8%	0.16	42 / 504
ovary	21%	8.28	38 / 180	47%	1.21	202 / 430
blood vessel	56%	26.95	754 / 1335	0%	0	0 / 0
heart	52%	19.96	447 / 861	0%	0	0 / 0
adrenal gland	21%	6.62	55 / 258	6%	0.11	14 / 230
lymph node	0%	0	0 / 0	14%	0.25	4 / 29
muscle	13%	4.18	103 / 803	0%	0	0 / 0
liver	7%	2.40	16 / 226	2%	0.04	9 / 406
tonsil	0%	0	0 / 0	9%	0.18	4 / 45
eye	0%	0	0 / 0	8%	0.81	6 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007601	Biological process	visual perception
GO_0098703	Biological process	calcium ion import across plasma membrane
GO_0050908	Biological process	detection of light stimulus involved in visual perception
GO_0005891	Cellular component	voltage-gated calcium channel complex
GO_0043204	Cellular component	perikaryon
GO_0001750	Cellular component	photoreceptor outer segment
GO_0016020	Cellular component	membrane
GO_0008331	Molecular function	high voltage-gated calcium channel activity
GO_0005245	Molecular function	voltage-gated calcium channel activity
GO_0046872	Molecular function	metal ion binding

Gene name	CACNA1F
Protein name	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage-gated calcium channel subunit alpha Cav1.4) Calcium voltage-gated channel subunit alpha1 F
Synonyms	CACNAF1
Description	FUNCTION: [Isoform 1]: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1F gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines. Activates at more negative voltages and does not undergo calcium-dependent inactivation (CDI), due to incoming calcium ions, during depolarization. .; FUNCTION: [Isoform 4]: Voltage-dependent L-type calcium channel activates at more hyperpolarized voltages and exhibits a robust calcium-dependent inactivation (CDI), due to incoming calcium ions, during depolarizations. .; FUNCTION: [Isoform 6]: Voltage-dependent L-type calcium channel activates at more hyperpolarized voltages and exhibits a robust calcium-dependent inactivation (CDI), due to incoming calcium ions, during depolarizations. .
Accessions	ENST00000376265.2 [O60840-1] ENST00000376251.5 [O60840-4] ENST00000323022.10 [O60840-2] O60840 H7C549 ENST00000486943.1

CACNA1F report