Name | Number of supported studies | Average coverage | |
---|---|---|---|
classical monocyte | 15 studies | 33% ± 15% | |
monocyte | 7 studies | 26% ± 8% | |
non-classical monocyte | 3 studies | 26% ± 5% | |
myeloid cell | 3 studies | 37% ± 9% |
Insufficient scRNA-seq data for expression of BST1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 99% | 576.20 | 456 / 459 | 93% | 5.79 | 1038 / 1118 |
ovary | 98% | 388.80 | 177 / 180 | 89% | 9.08 | 381 / 430 |
skin | 92% | 411.81 | 1672 / 1809 | 94% | 11.97 | 445 / 472 |
kidney | 99% | 409.53 | 88 / 89 | 87% | 8.73 | 785 / 901 |
lung | 100% | 761.80 | 576 / 578 | 86% | 6.36 | 989 / 1155 |
bladder | 100% | 816.57 | 21 / 21 | 79% | 9.25 | 398 / 504 |
intestine | 97% | 400.99 | 939 / 966 | 74% | 5.20 | 390 / 527 |
thymus | 95% | 314.32 | 620 / 653 | 66% | 2.56 | 400 / 605 |
uterus | 98% | 362.45 | 166 / 170 | 46% | 3.08 | 212 / 459 |
stomach | 45% | 125.82 | 163 / 359 | 81% | 4.94 | 231 / 286 |
esophagus | 80% | 216.75 | 1160 / 1445 | 45% | 1.91 | 83 / 183 |
prostate | 80% | 223.45 | 197 / 245 | 39% | 1.25 | 194 / 502 |
adrenal gland | 64% | 128.70 | 165 / 258 | 46% | 1.75 | 105 / 230 |
liver | 61% | 131.85 | 138 / 226 | 41% | 2.43 | 167 / 406 |
adipose | 100% | 1030.54 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 1063.56 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 8.01 | 1 / 1 |
blood vessel | 100% | 636.30 | 1333 / 1335 | 0% | 0 | 0 / 0 |
pancreas | 6% | 11.49 | 19 / 328 | 92% | 10.37 | 164 / 178 |
lymph node | 0% | 0 | 0 / 0 | 93% | 7.77 | 27 / 29 |
heart | 85% | 485.79 | 730 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 81% | 4957.42 | 755 / 929 | 0% | 0 | 0 / 0 |
brain | 14% | 20.90 | 364 / 2642 | 54% | 2.94 | 382 / 705 |
eye | 0% | 0 | 0 / 0 | 66% | 3.34 | 53 / 80 |
tonsil | 0% | 0 | 0 / 0 | 53% | 1.85 | 24 / 45 |
muscle | 16% | 25.29 | 125 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_2001044 | Biological process | regulation of integrin-mediated signaling pathway |
GO_0007165 | Biological process | signal transduction |
GO_0002691 | Biological process | regulation of cellular extravasation |
GO_0090322 | Biological process | regulation of superoxide metabolic process |
GO_0050727 | Biological process | regulation of inflammatory response |
GO_0001952 | Biological process | regulation of cell-matrix adhesion |
GO_0090022 | Biological process | regulation of neutrophil chemotaxis |
GO_0006959 | Biological process | humoral immune response |
GO_0050730 | Biological process | regulation of peptidyl-tyrosine phosphorylation |
GO_0050848 | Biological process | regulation of calcium-mediated signaling |
GO_0030890 | Biological process | positive regulation of B cell proliferation |
GO_0008284 | Biological process | positive regulation of cell population proliferation |
GO_0032956 | Biological process | regulation of actin cytoskeleton organization |
GO_0005576 | Cellular component | extracellular region |
GO_0035579 | Cellular component | specific granule membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0098552 | Cellular component | side of membrane |
GO_0001931 | Cellular component | uropod |
GO_0003953 | Molecular function | NAD+ nucleosidase activity |
GO_0016849 | Molecular function | phosphorus-oxygen lyase activity |
GO_0016740 | Molecular function | transferase activity |
GO_0061809 | Molecular function | NAD+ nucleotidase, cyclic ADP-ribose generating |
Gene name | BST1 |
Protein name | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 (EC 3.2.2.6) (ADP-ribosyl cyclase 2) (Bone marrow stromal cell antigen 1) (BST-1) (Cyclic ADP-ribose hydrolase 2) (cADPR hydrolase 2) (CD antigen CD157) ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase (EC 3.2.2.6) |
Synonyms | |
Description | FUNCTION: Catalyzes both the synthesis of cyclic ADP-beta-D-ribose (cADPR) from NAD(+), and its hydrolysis to ADP-D-ribose (ADPR) . Cyclic ADPR is known to serve as an endogenous second messenger that elicits calcium release from intracellular stores, and thus regulates the mobilization of intracellular calcium (Probable). May be involved in pre-B-cell growth (Probable). . |
Accessions | ENST00000265016.9 [Q10588-1] H0Y8G4 A0A386NEX7 A6NC48 H0Y984 ENST00000382346.7 ENST00000514989.1 ENST00000514445.5 Q10588 ENST00000505785.5 H0Y9Q9 |