BRD9 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006338Biological processchromatin remodeling
GO_0045596Biological processnegative regulation of cell differentiation
GO_0008284Biological processpositive regulation of cell population proliferation
GO_1902459Biological processpositive regulation of stem cell population maintenance
GO_0008150Biological processbiological_process
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0140288Cellular componentGBAF complex
GO_0016514Cellular componentSWI/SNF complex
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0070577Molecular functionlysine-acetylated histone binding
GO_0005515Molecular functionprotein binding
GO_0003676Molecular functionnucleic acid binding

IV. Literature review

[source]
Gene nameBRD9
Protein nameBromodomain containing 9
Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS-40.8)
SynonymsUNQ3040/PRO9856
DescriptionFUNCTION: Plays a role in chromatin remodeling and regulation of transcription . Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated . Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner . Orchestrates also the RAD51-RAD54 complex formation and thereby plays a role in homologous recombination (HR) . .

AccessionsH0YAW8
H0YBR9
H0YBF1
ENST00000519112.5
ENST00000523139.5
C9JBY0
ENST00000466684.5
ENST00000518251.1
ENST00000489093.1
F2Z2E8
ENST00000518250.5
ENST00000483173.5 [Q9H8M2-6]
ENST00000467963.6 [Q9H8M2-5]
ENST00000490814.6
Q9H8M2
ENST00000489816.5
H0YBX9
ENST00000495265.5
ENST00000487688.1