BRAT1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of BRAT1 at tissue level.

III. Associated gene sets

GO_0006915Biological processapoptotic process
GO_0051646Biological processmitochondrion localization
GO_0006974Biological processDNA damage response
GO_0008283Biological processcell population proliferation
GO_0001934Biological processpositive regulation of protein phosphorylation
GO_0010212Biological processresponse to ionizing radiation
GO_0016477Biological processcell migration
GO_0006006Biological processglucose metabolic process
GO_0030307Biological processpositive regulation of cell growth
GO_0005654Cellular componentnucleoplasm
GO_0016020Cellular componentmembrane
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameBRAT1
Protein nameBRCA1 associated ATM activator 1
BRCA1-associated ATM activator 1 (BRCA1-associated protein required for ATM activation protein 1)
SynonymsBAAT1
C7orf27
DescriptionFUNCTION: Involved in DNA damage response; activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress . Plays a role in regulating mitochondrial function and cell proliferation . Required for protein stability of MTOR and MTOR-related proteins, and cell cycle progress by growth factors . .

AccessionsENST00000421712.1
ENST00000340611.9 [Q6PJG6-1]
F8WDN5
Q6PJG6