I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| retina horizontal cell | 5 studies | 36% ± 9% | |
| astrocyte | 3 studies | 17% ± 3% | |
| glutamatergic neuron | 3 studies | 35% ± 13% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| retina horizontal cell | 5 studies | 36% ± 9% | |
| astrocyte | 3 studies | 17% ± 3% | |
| glutamatergic neuron | 3 studies | 35% ± 13% |
Insufficient scRNA-seq data for expression of BEGAIN at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 98% | 3367.01 | 2590 / 2642 | 80% | 3.69 | 566 / 705 |
| pancreas | 100% | 1628.09 | 328 / 328 | 40% | 1.08 | 72 / 178 |
| prostate | 90% | 557.62 | 221 / 245 | 25% | 0.42 | 125 / 502 |
| adrenal gland | 40% | 305.62 | 102 / 258 | 68% | 23.13 | 157 / 230 |
| ovary | 85% | 639.64 | 153 / 180 | 23% | 0.48 | 97 / 430 |
| spleen | 95% | 757.92 | 230 / 241 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 95% | 5.22 | 76 / 80 |
| uterus | 64% | 397.21 | 108 / 170 | 26% | 1.19 | 119 / 459 |
| esophagus | 59% | 463.02 | 849 / 1445 | 27% | 0.65 | 50 / 183 |
| breast | 43% | 198.21 | 196 / 459 | 18% | 0.46 | 200 / 1118 |
| skin | 11% | 37.19 | 206 / 1809 | 44% | 1.71 | 209 / 472 |
| lung | 32% | 115.71 | 184 / 578 | 16% | 0.46 | 180 / 1155 |
| bladder | 38% | 134.90 | 8 / 21 | 8% | 0.26 | 39 / 504 |
| intestine | 23% | 89.99 | 225 / 966 | 14% | 0.35 | 76 / 527 |
| thymus | 15% | 47.58 | 97 / 653 | 17% | 0.79 | 102 / 605 |
| heart | 24% | 86.24 | 208 / 861 | 0% | 0 | 0 / 0 |
| stomach | 11% | 44.23 | 39 / 359 | 13% | 0.35 | 37 / 286 |
| adipose | 20% | 80.53 | 243 / 1204 | 0% | 0 | 0 / 0 |
| liver | 1% | 2.61 | 2 / 226 | 13% | 0.51 | 54 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 14% | 0.20 | 4 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 9% | 0.11 | 4 / 45 |
| kidney | 6% | 17.44 | 5 / 89 | 2% | 0.05 | 20 / 901 |
| peripheral blood | 7% | 25.70 | 67 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 3% | 10.30 | 38 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 2% | 7.87 | 17 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0098962 | Biological process | regulation of postsynaptic neurotransmitter receptor activity |
| GO_0045202 | Cellular component | synapse |
| GO_0016020 | Cellular component | membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005515 | Molecular function | protein binding |
| Gene name | BEGAIN |
| Protein name | Brain enriched guanylate kinase associated Brain enriched guanylate kinase associated (Likely ortholog of rat brain-enriched guanylate kinase-associated protein, isoform CRA_a) Brain-enriched guanylate kinase-associated protein |
| Synonyms | KIAA1446 hCG_25026 |
| Description | FUNCTION: May sustain the structure of the postsynaptic density (PSD). |
| Accessions | ENST00000355173.7 G3V3R5 ENST00000553553 A0A1B0GTT1 ENST00000554356.6 A0A1B0GVM0 G3V2K4 ENST00000556188.6 ENST00000557378.6 ENST00000637716.2 ENST00000554140.3 ENST00000637646.1 G3V3A2 ENST00000557378 ENST00000556188 ENST00000553553.6 G3V536 G3V3S3 Q9BUH8 |
