BAIAP3 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of BAIAP3 at tissue level.

III. Associated gene sets

GO_1990502Biological processdense core granule maturation
GO_0050795Biological processregulation of behavior
GO_0035774Biological processpositive regulation of insulin secretion involved in cellular response to glucose stimulus
GO_0042147Biological processretrograde transport, endosome to Golgi
GO_1905413Biological processregulation of dense core granule exocytosis
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0006887Biological processexocytosis
GO_0001956Biological processpositive regulation of neurotransmitter secretion
GO_0032228Biological processregulation of synaptic transmission, GABAergic
GO_0098793Cellular componentpresynapse
GO_0031902Cellular componentlate endosome membrane
GO_0005886Cellular componentplasma membrane
GO_0031901Cellular componentearly endosome membrane
GO_0055038Cellular componentrecycling endosome membrane
GO_0032588Cellular componenttrans-Golgi network membrane
GO_0098982Cellular componentGABA-ergic synapse
GO_0099503Cellular componentsecretory vesicle
GO_0005829Cellular componentcytosol
GO_0031045Cellular componentdense core granule
GO_0005543Molecular functionphospholipid binding
GO_0000149Molecular functionSNARE binding
GO_0005509Molecular functioncalcium ion binding
GO_0005515Molecular functionprotein binding
GO_0019905Molecular functionsyntaxin binding

IV. Literature review

[source]
Gene nameBAIAP3
Protein nameBAI1 associated protein 3
BAI1-associated protein 3 (BAP3) (Brain-specific angiogenesis inhibitor I-associated protein 3)
SynonymsKIAA0734
DescriptionFUNCTION: Functions in endosome to Golgi retrograde transport. In response to calcium influx, may interact with SNARE fusion receptors and membrane phospholipids to mediate endosome fusion with the trans-Golgi network. By promoting the recycling of secretory vesicle transmembrane proteins, it indirectly controls dense-core secretory vesicle biogenesis, maturation and their ability to mediate the constitutive and regulated secretion of neurotransmitters and hormones. May regulate behavior and food intake by controlling calcium-stimulated exocytosis of neurotransmitters including NPY and serotonin and hormones like insulin . Proposed to play a role in hypothalamic neuronal firing by modulating gamma-aminobutyric acid (GABA)ergic inhibitory neurotransmission (By similarity). .

AccessionsA0AA34QW15
A0AA34QVV4
A0AA34QVM4
ENST00000711105.1
A0AA34QVY1
ENST00000711104.1
ENST00000711107.1
ENST00000568887.5 [O94812-5]
H3BPP9
ENST00000421665.6 [O94812-7]
ENST00000564213.2
ENST00000324385.9 [O94812-1]
A0AA34QW16
ENST00000711103.1
A0AA34QVM8
ENST00000562208.5 [O94812-3]
O94812
ENST00000397488.6 [O94812-2]
ENST00000711109.1
ENST00000711108.1
A0AA34QVV7
ENST00000711110.1
ENST00000561793.2
A0AA34QVM9
A0AA34QVM2
ENST00000711102.1
ENST00000426824.8 [O94812-6]
A0AA34QVY3
ENST00000711106.1