AVIL | OmnibusX

Name	Number of supported studies	Average coverage
brush cell	4 studies	65% ± 18%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of AVIL at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	380.96	180 / 180	95%	5.05	410 / 430
breast	98%	327.17	452 / 459	95%	3.26	1061 / 1118
pancreas	98%	303.93	320 / 328	96%	5.05	170 / 178
thymus	100%	831.06	653 / 653	93%	3.70	561 / 605
lung	98%	482.33	566 / 578	92%	3.97	1059 / 1155
brain	90%	386.19	2383 / 2642	99%	10.85	700 / 705
esophagus	96%	256.89	1388 / 1445	92%	3.12	169 / 183
adrenal gland	99%	568.24	255 / 258	90%	2.98	206 / 230
intestine	100%	467.70	966 / 966	87%	2.99	460 / 527
uterus	100%	303.45	170 / 170	85%	2.60	388 / 459
bladder	100%	350.00	21 / 21	84%	3.19	423 / 504
stomach	96%	273.97	345 / 359	87%	4.51	248 / 286
prostate	100%	457.15	245 / 245	79%	1.56	398 / 502
kidney	100%	500.16	89 / 89	79%	2.12	714 / 901
skin	95%	237.00	1727 / 1809	67%	1.71	318 / 472
liver	90%	284.25	203 / 226	61%	3.35	246 / 406
ureter	0%	0	0 / 0	100%	1.70	1 / 1
muscle	100%	707.42	801 / 803	0%	0	0 / 0
spleen	99%	478.12	239 / 241	0%	0	0 / 0
blood vessel	98%	289.14	1305 / 1335	0%	0	0 / 0
adipose	97%	328.99	1163 / 1204	0%	0	0 / 0
heart	94%	228.84	811 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	67%	1.67	30 / 45
lymph node	0%	0	0 / 0	59%	1.78	17 / 29
peripheral blood	56%	425.75	520 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	44%	0.79	35 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0060271	Biological process	cilium assembly
GO_0051016	Biological process	barbed-end actin filament capping
GO_0010976	Biological process	positive regulation of neuron projection development
GO_0010592	Biological process	positive regulation of lamellipodium assembly
GO_1900480	Biological process	regulation of diacylglycerol biosynthetic process
GO_0008154	Biological process	actin polymerization or depolymerization
GO_0051014	Biological process	actin filament severing
GO_0007015	Biological process	actin filament organization
GO_0007399	Biological process	nervous system development
GO_0043005	Cellular component	neuron projection
GO_0005884	Cellular component	actin filament
GO_0005925	Cellular component	focal adhesion
GO_0015629	Cellular component	actin cytoskeleton
GO_0005737	Cellular component	cytoplasm
GO_0042995	Cellular component	cell projection
GO_0030424	Cellular component	axon
GO_0030027	Cellular component	lamellipodium
GO_0005546	Molecular function	phosphatidylinositol-4,5-bisphosphate binding
GO_0051015	Molecular function	actin filament binding
GO_0071933	Molecular function	Arp2/3 complex binding
GO_0003779	Molecular function	actin binding
GO_0005515	Molecular function	protein binding

Gene name	AVIL
Protein name	Advillin Advillin (p92)
Synonyms
Description	FUNCTION: Ca(2+)-regulated actin-binding protein which plays an important role in actin bundling . May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis. In podocytes, controls lamellipodia formation through the regulation of EGF-induced diacylglycerol generation by PLCE1 and ARP2/3 complex assembly . .
Accessions	F8VVU1 ENST00000549851.5 F8VNY0 ENST00000549994.2 [O75366-1] O75366 ENST00000257861.7 [O75366-1] ENST00000549994

AVIL report