I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| astrocyte | 4 studies | 24% ± 5% | |
| plasma cell | 3 studies | 23% ± 10% | |
| GABAergic neuron | 3 studies | 44% ± 5% | |
| glutamatergic neuron | 3 studies | 50% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 4 studies | 24% ± 5% | |
| plasma cell | 3 studies | 23% ± 10% | |
| GABAergic neuron | 3 studies | 44% ± 5% | |
| glutamatergic neuron | 3 studies | 50% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 29% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 6162.13 | 244 / 245 | 98% | 36.66 | 493 / 502 |
| thymus | 100% | 4925.33 | 651 / 653 | 95% | 20.17 | 577 / 605 |
| breast | 99% | 4458.15 | 455 / 459 | 95% | 21.72 | 1063 / 1118 |
| lung | 100% | 5468.95 | 577 / 578 | 91% | 17.88 | 1048 / 1155 |
| skin | 89% | 4174.00 | 1616 / 1809 | 100% | 63.47 | 472 / 472 |
| brain | 86% | 3288.71 | 2273 / 2642 | 99% | 18.13 | 699 / 705 |
| ovary | 100% | 9105.29 | 180 / 180 | 80% | 11.78 | 345 / 430 |
| esophagus | 94% | 6549.04 | 1354 / 1445 | 74% | 12.32 | 136 / 183 |
| adrenal gland | 91% | 2109.38 | 236 / 258 | 76% | 19.98 | 175 / 230 |
| uterus | 100% | 10992.28 | 170 / 170 | 65% | 15.63 | 300 / 459 |
| intestine | 99% | 4845.56 | 960 / 966 | 55% | 6.83 | 289 / 527 |
| bladder | 100% | 5903.86 | 21 / 21 | 53% | 7.91 | 266 / 504 |
| kidney | 70% | 1594.98 | 62 / 89 | 80% | 12.50 | 724 / 901 |
| stomach | 84% | 3631.17 | 300 / 359 | 63% | 9.93 | 180 / 286 |
| pancreas | 42% | 627.21 | 138 / 328 | 92% | 19.30 | 163 / 178 |
| blood vessel | 100% | 11208.28 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 100% | 5385.56 | 241 / 241 | 0% | 0 | 0 / 0 |
| adipose | 100% | 4947.11 | 1202 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 98% | 47.51 | 78 / 80 |
| heart | 86% | 2345.50 | 740 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 76% | 15.22 | 22 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 76% | 11.17 | 34 / 45 |
| peripheral blood | 66% | 1679.08 | 615 / 929 | 0% | 0 | 0 / 0 |
| liver | 11% | 156.42 | 24 / 226 | 44% | 5.01 | 178 / 406 |
| muscle | 11% | 187.33 | 92 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0034220 | Biological process | monoatomic ion transmembrane transport |
| GO_0007030 | Biological process | Golgi organization |
| GO_0045332 | Biological process | phospholipid translocation |
| GO_0005802 | Cellular component | trans-Golgi network |
| GO_0005730 | Cellular component | nucleolus |
| GO_1990531 | Cellular component | phospholipid-translocating ATPase complex |
| GO_0005829 | Cellular component | cytosol |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0140345 | Molecular function | phosphatidylcholine flippase activity |
| GO_0090554 | Molecular function | phosphatidylcholine floppase activity |
| GO_0005524 | Molecular function | ATP binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0016887 | Molecular function | ATP hydrolysis activity |
| GO_0000287 | Molecular function | magnesium ion binding |
| GO_0140326 | Molecular function | ATPase-coupled intramembrane lipid transporter activity |
| Gene name | ATP8B2 |
| Protein name | Phospholipid-transporting ATPase ID (EC 7.6.2.1) (ATPase class I type 8B member 2) (P4-ATPase flippase complex alpha subunit ATP8B2) Phospholipid-transporting ATPase (EC 7.6.2.1) ATP8B2 protein |
| Synonyms | ATPID KIAA1137 |
| Description | FUNCTION: Catalytic component of P4-ATPase flippase complex, which catalyzes the hydrolysis of ATP coupled to the transport of phosphatidylcholine (PC) from the outer to the inner leaflet of the plasma membrane. May contribute to the maintenance of membrane lipid asymmetry. . |
| Accessions | ENST00000672630.1 [P98198-3] ENST00000368487.7 [P98198-4] Q6P3T1 P98198 ENST00000368489.6 A0A5K1VW70 ENST00000696573.1 [P98198-1] |
