Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 10 studies | 28% ± 12% | |
oligodendrocyte precursor cell | 9 studies | 32% ± 15% | |
oligodendrocyte | 8 studies | 31% ± 10% | |
glutamatergic neuron | 6 studies | 50% ± 28% | |
epithelial cell | 5 studies | 26% ± 15% | |
GABAergic neuron | 5 studies | 44% ± 21% | |
astrocyte | 5 studies | 34% ± 11% | |
fibroblast | 5 studies | 23% ± 8% | |
endothelial cell of lymphatic vessel | 4 studies | 24% ± 6% | |
macrophage | 4 studies | 21% ± 4% | |
smooth muscle cell | 4 studies | 17% ± 0% | |
neuron | 3 studies | 27% ± 12% | |
microglial cell | 3 studies | 22% ± 2% | |
retinal ganglion cell | 3 studies | 22% ± 5% | |
plasma cell | 3 studies | 20% ± 6% | |
hepatocyte | 3 studies | 33% ± 12% | |
granule cell | 3 studies | 17% ± 2% | |
interneuron | 3 studies | 54% ± 23% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 8 studies | 40% ± 21% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 3908.82 | 1445 / 1445 | 100% | 13.52 | 183 / 183 |
prostate | 100% | 4426.01 | 245 / 245 | 100% | 13.00 | 501 / 502 |
breast | 100% | 4705.91 | 459 / 459 | 99% | 12.11 | 1111 / 1118 |
lung | 100% | 4417.26 | 578 / 578 | 99% | 8.52 | 1144 / 1155 |
thymus | 100% | 5585.87 | 653 / 653 | 99% | 10.19 | 599 / 605 |
pancreas | 100% | 4702.12 | 328 / 328 | 99% | 8.84 | 176 / 178 |
brain | 99% | 3989.95 | 2616 / 2642 | 100% | 10.71 | 703 / 705 |
kidney | 100% | 3234.40 | 89 / 89 | 98% | 9.78 | 886 / 901 |
stomach | 100% | 3611.58 | 359 / 359 | 98% | 8.03 | 281 / 286 |
intestine | 100% | 4499.46 | 966 / 966 | 97% | 6.89 | 512 / 527 |
adrenal gland | 100% | 4078.11 | 258 / 258 | 97% | 10.12 | 223 / 230 |
bladder | 100% | 4101.38 | 21 / 21 | 97% | 6.30 | 488 / 504 |
uterus | 100% | 5780.82 | 170 / 170 | 97% | 7.10 | 444 / 459 |
skin | 100% | 6560.65 | 1809 / 1809 | 95% | 9.94 | 450 / 472 |
ovary | 100% | 4938.49 | 180 / 180 | 95% | 5.88 | 408 / 430 |
liver | 100% | 3573.37 | 226 / 226 | 93% | 6.07 | 377 / 406 |
adipose | 100% | 4292.68 | 1204 / 1204 | 0% | 0 | 0 / 0 |
muscle | 100% | 3566.48 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 4521.50 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 2.36 | 1 / 1 |
blood vessel | 100% | 4104.57 | 1334 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 6.87 | 44 / 45 |
heart | 96% | 2227.63 | 830 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 90% | 6.13 | 26 / 29 |
eye | 0% | 0 | 0 / 0 | 89% | 6.42 | 71 / 80 |
peripheral blood | 67% | 1363.98 | 626 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0000422 | Biological process | autophagy of mitochondrion |
GO_0120009 | Biological process | intermembrane lipid transfer |
GO_0034727 | Biological process | piecemeal microautophagy of the nucleus |
GO_0061709 | Biological process | reticulophagy |
GO_0030242 | Biological process | autophagy of peroxisome |
GO_0061723 | Biological process | glycophagy |
GO_0000045 | Biological process | autophagosome assembly |
GO_0034045 | Cellular component | phagophore assembly site membrane |
GO_0005811 | Cellular component | lipid droplet |
GO_0000407 | Cellular component | phagophore assembly site |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0061908 | Cellular component | phagophore |
GO_0043495 | Molecular function | protein-membrane adaptor activity |
GO_0120013 | Molecular function | lipid transfer activity |
GO_0032266 | Molecular function | phosphatidylinositol-3-phosphate binding |
Gene name | ATG2B |
Protein name | Autophagy-related protein 2 homolog B Alternative protein ATG2B |
Synonyms | C14orf103 |
Description | FUNCTION: Lipid transfer protein required for both autophagosome formation and regulation of lipid droplet morphology and dispersion . Tethers the edge of the isolation membrane (IM) to the endoplasmic reticulum (ER) and mediates direct lipid transfer from ER to IM for IM expansion . Binds to the ER exit site (ERES), which is the membrane source for autophagosome formation, and extracts phospholipids from the membrane source and transfers them to ATG9 (ATG9A or ATG9B) to the IM for membrane expansion (By similarity). Lipid transfer activity is enhanced by WDR45/WIPI4, which promotes ATG2B-association with phosphatidylinositol 3-monophosphate (PI3P)-containing membranes . . |
Accessions | L8E8U7 ENST00000359933.6 Q96BY7 |