Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 11 studies | 31% ± 11% | |
endothelial cell | 5 studies | 28% ± 7% | |
oligodendrocyte precursor cell | 5 studies | 25% ± 7% | |
epithelial cell | 4 studies | 33% ± 10% | |
astrocyte | 4 studies | 22% ± 4% | |
plasmablast | 3 studies | 25% ± 9% | |
neuron | 3 studies | 27% ± 13% | |
retinal cone cell | 3 studies | 21% ± 3% | |
GABAergic neuron | 3 studies | 37% ± 9% | |
glutamatergic neuron | 3 studies | 45% ± 13% | |
abnormal cell | 3 studies | 20% ± 3% | |
goblet cell | 3 studies | 30% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 4228.94 | 1445 / 1445 | 100% | 45.44 | 183 / 183 |
kidney | 100% | 4245.31 | 89 / 89 | 100% | 37.49 | 901 / 901 |
liver | 100% | 3294.71 | 226 / 226 | 100% | 29.86 | 406 / 406 |
ovary | 100% | 4461.86 | 180 / 180 | 100% | 50.13 | 430 / 430 |
pancreas | 100% | 3985.14 | 328 / 328 | 100% | 40.17 | 178 / 178 |
prostate | 100% | 5414.20 | 245 / 245 | 100% | 44.18 | 502 / 502 |
skin | 100% | 5252.62 | 1809 / 1809 | 100% | 49.86 | 472 / 472 |
stomach | 100% | 4320.99 | 359 / 359 | 100% | 37.16 | 286 / 286 |
thymus | 100% | 5727.64 | 653 / 653 | 100% | 46.26 | 605 / 605 |
brain | 100% | 6863.76 | 2641 / 2642 | 100% | 65.36 | 705 / 705 |
breast | 100% | 4974.18 | 459 / 459 | 100% | 48.82 | 1117 / 1118 |
uterus | 100% | 4913.26 | 170 / 170 | 100% | 36.38 | 458 / 459 |
lung | 100% | 3955.28 | 577 / 578 | 100% | 39.96 | 1154 / 1155 |
intestine | 100% | 4220.08 | 966 / 966 | 99% | 34.70 | 524 / 527 |
adrenal gland | 100% | 6012.08 | 258 / 258 | 99% | 45.76 | 228 / 230 |
bladder | 100% | 4369.10 | 21 / 21 | 99% | 31.80 | 499 / 504 |
adipose | 100% | 4840.20 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 59.62 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 37.97 | 29 / 29 |
spleen | 100% | 5387.17 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 42.18 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 12.52 | 1 / 1 |
blood vessel | 100% | 4852.40 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 3622.30 | 855 / 861 | 0% | 0 | 0 / 0 |
muscle | 99% | 2971.19 | 797 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 98% | 3639.41 | 914 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_1903059 | Biological process | regulation of protein lipidation |
GO_0000045 | Biological process | autophagosome assembly |
GO_0034497 | Biological process | protein localization to phagophore assembly site |
GO_0034727 | Biological process | piecemeal microautophagy of the nucleus |
GO_0010508 | Biological process | positive regulation of autophagy |
GO_0000423 | Biological process | mitophagy |
GO_1903955 | Biological process | positive regulation of protein targeting to mitochondrion |
GO_0098780 | Biological process | response to mitochondrial depolarisation |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0005739 | Cellular component | mitochondrion |
GO_0034045 | Cellular component | phagophore assembly site membrane |
GO_0005829 | Cellular component | cytosol |
GO_1990316 | Cellular component | Atg1/ULK1 kinase complex |
GO_0000407 | Cellular component | phagophore assembly site |
GO_0005776 | Cellular component | autophagosome |
GO_0005737 | Cellular component | cytoplasm |
GO_0019887 | Molecular function | protein kinase regulator activity |
GO_0019901 | Molecular function | protein kinase binding |
GO_0043539 | Molecular function | protein serine/threonine kinase activator activity |
GO_0005515 | Molecular function | protein binding |
Gene name | ATG13 |
Protein name | Autophagy-related protein 13 Autophagy related 13 |
Synonyms | KIAA0652 |
Description | FUNCTION: Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation. . FUNCTION: Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation. . FUNCTION: Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation. . FUNCTION: Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation. . FUNCTION: Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation. . |
Accessions | J3QRL1 ENST00000395549.3 A0A1B0GXJ3 H0YCL5 ENST00000525009.5 ENST00000581438.5 J3QR83 ENST00000532067.1 ENST00000582547.5 ENST00000580238.5 ENST00000528494.5 [O75143-5] J3QLH7 J3KRU6 ENST00000529395.1 ENST00000524625.5 [O75143-2] H0YEM7 ENST00000359513.8 [O75143-1] J3QR16 ENST00000583249.5 H0YDR0 ENST00000530500.5 [O75143-4] ENST00000578626.5 ENST00000529655.5 [O75143-2] ENST00000581416.5 H0YF43 O75143 J9JIF6 ENST00000683050.1 [O75143-5] ENST00000533325.5 E9PPR2 ENST00000531933.1 ENST00000526508.5 [O75143-1] J3KST9 ENST00000577256.5 |